PrEP Decisional Aid for HIV Prevention
(DASH Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new app designed to help individuals using HIV self-test kits learn about PrEP, a medication that prevents HIV, and decide if it suits them. By integrating this tool with self-testing, the trial aims to simplify understanding of options and access to PrEP if needed. Participants will be divided into two groups: one using the app and one not, to evaluate the app's effectiveness. This trial may suit those comfortable with English, with internet access, who are HIV negative, and have never used PrEP. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could simplify access to HIV prevention methods.
Do I have to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It focuses on people who have never used PrEP before.
What prior data suggests that the PrEP Decisional Aid is safe for users?
Research has shown that the PrEP Decisional Aid (DASH app) helps people make informed decisions about using PrEP, a proven method to prevent HIV. Studies have demonstrated that PrEP is safe and effective, reducing the risk of contracting HIV by up to 99% when taken as directed. This makes it a well-accepted option for those at risk of HIV.
Regarding the DASH app, no safety concerns exist because it is a digital tool that provides information and aids decision-making. It is not a medicine or treatment; instead, it helps users understand and access PrEP. Since the app assists with decisions rather than directly impacting health, it is considered safe to use.12345Why are researchers excited about this trial?
Researchers are excited about the PrEP Decisional Aid for dissemination with Self-administered HIV test kits (DASH) because it offers a novel approach to HIV prevention. Unlike traditional methods that rely on in-person consultations and guidance, DASH provides a digital tool that can be easily accessed through an app. This approach empowers individuals by offering them information and reminders in a user-friendly way, potentially increasing adherence to PrEP usage. The convenience and accessibility of this method could significantly enhance the reach and effectiveness of HIV prevention strategies, especially among populations that face barriers to accessing healthcare services.
What evidence suggests that the DASH app is effective for increasing PrEP uptake among HIV self-test users?
Research shows that PrEP (pre-exposure prophylaxis) effectively prevents HIV when taken correctly. Studies indicate that daily PrEP use can reduce the risk of contracting HIV from sex by 99% and from injecting drugs by at least 74%. In this trial, participants in the DASH Intervention Arm will access the DASH app, which helps individuals decide if PrEP suits them by guiding them through the process and considering their personal needs and values. Previous research has shown that tools like this can increase PrEP use by identifying those at risk and encouraging them to start treatment. This method empowers users to take charge of their health and lower their risk of HIV infection.23678
Who Is on the Research Team?
K Rivet Amico, PhD
Principal Investigator
University of Michigan
Are You a Good Fit for This Trial?
This trial is for people who are using at-home HIV self-test kits through the CDC's Together TakeMeHome program. Participants should be interested in learning more about HIV prevention and considering PrEP as an option.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pilot Study
Participants are recruited and randomly assigned to either the DASH intervention arm or the comparison condition. They complete online surveys assessing PrEP awareness, knowledge, intentions, and use.
Follow-up
Participants are monitored for changes in PrEP uptake, knowledge, and other related factors. Additional qualitative interviews are conducted with a subset of participants.
What Are the Treatments Tested in This Trial?
Interventions
- PrEP Decisional Aid for dissemination with Self-administered HIV test kits (DASH)
Trial Overview
The study is testing a new, interactive website (DASH app) designed to help users of HIV self-test kits learn about PrEP, decide if it's right for them, and connect with local or online resources. Participants will be randomly assigned to use this tool or not.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants receive access to the DASH app through an emailed link with reminders to use the link at least one during the 3 month study period
Participants in the comparison condition do not receive additional PrEP related information through the project- but have access to PrEP information from the self-test kit and other programs that are available.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator
Citations
Decision Support Tool to Improve Decision-Making for HIV Pre ...
Our study aimed to develop a DST to improve PrEP decision-making for Black clients and to evaluate the tool's acceptability and usability.
2.
marsal.umich.edu
marsal.umich.edu/grants-awards/self-administered-prep-decisional-aid-dissemination-hiv-self-test-kits-dashA self-administered PrEP Decisional Aid for dissemination ...
It will help to raise awareness around PrEP and guide people through a PrEP decision-making process that matches their needs and values, and ...
The HIV Data Decision Maker
This tool allows the user to explore essential datasets, practical tools, and best practices for planning, monitoring and evaluating HIV prevention programmes.
A Type 3 Hybrid Effectiveness-Implementation Trial | AIDS and ...
This study sought to compare implementation and effectiveness outcomes for two delivery strategies of a digital HIV prevention intervention: ...
Study Details | NCT04855773 | Comparing Mobile Health ...
The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV ...
Patient-led decision-making for HIV preexposure prophylaxis
Few evidence-based clinical decision aids have been created for PrEP. An online clinical decision aid to help MSM and their primary care providers decide ...
7.
hiv.gov
hiv.gov/hiv-basics/hiv-prevention/using-hiv-medication-to-reduce-risk/pre-exposure-prophylaxisPre-Exposure Prophylaxis (PrEP)
Pre-exposure prophylaxis, also called PrEP, is a safe, effective prescription medicine that can reduce the risk of getting HIV by as much as 99%.
WHO PrEP Implementation Tool
This module provides information for people who are interested in taking PrEP to reduce their risk of acquiring HIV and people who are already taking PrEP – to ...
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