Nitrate Supplementation for Postmenopausal Women on Hormone Therapy
(BEET-MHT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study is examining whether short-term supplementation with inorganic nitrate in the form of beetroot juice can enhance vascular function in postmenopausal females taking hormone therapy compared to placebo.
Who Is on the Research Team?
Jason Allen
Principal Investigator
University of Virginia
Are You a Good Fit for This Trial?
This trial is for postmenopausal women who are currently taking hormone replacement therapy and experiencing hot flashes. Participants should generally be in good health, but specific inclusion or exclusion details were not provided.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Trial Overview
The study compares the effects of moderate vs. high intensity exercise, with or without beetroot juice (which contains nitrates), on blood vessel health in postmenopausal women using hormone therapy. There is also a group that does not exercise.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Participants will supplement with nitrate-rich beetroot juice (BRJ) for 3 days: 6.45 mmol of NO3 in the morning and 6.45 mmol in the evening for 2 days, and 12.9 mmol 2 hours before the lab visit. The order of intervention is also randomized.
Participants will supplement with nitrate-depleted beetroot juice (BRJ) for 3 days. This placebo is identical in color, taste, and packaging. The order of intervention is also randomized.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Virginia
Lead Sponsor
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