20 Participants NeededMy employer runs this trial

Movement Pattern Training for Polymyalgia Rheumatica

MH
Overseen ByMarcie Harris-Hayes, DPT, MSCI
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Washington University School of Medicine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a special type of physical therapy called Movement Pattern Training to assist people with polymyalgia rheumatica (PMR), a condition that causes joint pain and stiffness. The researchers aim to determine if this training can ease everyday tasks, reduce the need for certain medications, and strengthen muscles. Participants will either continue their usual care or receive personalized exercises to improve movement during daily activities. Suitable candidates have PMR with significant joint pain and can safely engage in physical activity. As an unphased trial, this study provides a unique opportunity to explore innovative therapy that could enhance daily life for PMR patients.

What prior data suggests that Movement Pattern Training is safe for people with polymyalgia rheumatica?

Research has shown that Movement Pattern Training is generally safe for people with polymyalgia rheumatica (PMR). Studies indicate that physiotherapy, including exercises like Movement Pattern Training, can enhance mobility. This training focuses on correcting movement patterns, which can reduce pain and improve daily activity performance.

Specific reports of negative effects from Movement Pattern Training itself are lacking. However, similar exercise programs for PMR have been well-tolerated. Research on exercise for PMR patients suggests that these programs are safe and acceptable when supervised by physiotherapists. This makes Movement Pattern Training a promising option for managing PMR symptoms with minimal risk.12345

Why are researchers excited about this trial?

Researchers are excited about Movement Pattern Training (MoveTrain) for polymyalgia rheumatica because it offers a unique approach compared to standard treatments like corticosteroids, which primarily manage inflammation. MoveTrain focuses on retraining how patients move during tasks that cause pain, such as getting out of bed or reaching overhead, by identifying and modifying the specific joint motions that trigger discomfort. This personalized, activity-specific training aims to improve daily function and potentially offer a sustainable way to manage pain without relying solely on medication.

What evidence suggests that Movement Pattern Training is effective for polymyalgia rheumatica?

Research has shown that movement pattern training, which participants in this trial may receive, can help people with polymyalgia rheumatica (PMR), a condition that causes joint pain and stiffness. An initial study found that patients who tried this training experienced noticeable improvements in pain and mobility. Patients completed over 91% of the exercises independently, indicating that they found the training easy to follow. Physical therapy, which uses similar techniques, is known to improve flexibility and help restore normal movement. These findings suggest that movement pattern training could be a promising way to manage PMR symptoms.678910

Are You a Good Fit for This Trial?

This trial is for people aged 50 or older who have been diagnosed with polymyalgia rheumatica (PMR) within the last 5 months. Participants should have shoulder pain, morning stiffness over 45 minutes, certain blood test results, and be on medication for PMR. They must also be able to give consent and not have other joint diseases.

Inclusion Criteria

I have pain in both of my shoulders.
A score ≥4 at diagnosis based on duration of morning stiffness >45 minutes (2 points), hip pain or limited range of motion (1 point), seronegative for rheumatoid factor and anti-CCP (2 points), absence of other joint involvement (1 point)
Able to give informed consent
See 5 more

Exclusion Criteria

I do not have any active infections that are not under control.
I have been diagnosed with a chronic nerve or muscle pain condition.
I am scheduled to have a major surgery during the study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo Movement Pattern Training to improve joint motion and reduce pain during daily activities

10 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Movement Pattern Training (MoveTrain)

Trial Overview

The study compares usual care for PMR with a personalized rehabilitation program called Movement Pattern Training (MoveTrain). The goal is to see if MoveTrain helps reduce pain, improve movement in daily life, lower medication use, and strengthen muscles.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Movement Pattern Training (MoveTrain)Experimental Treatment1 Intervention
Group II: Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Washington University School of Medicine

Lead Sponsor

Trials
2,027
Recruited
2,353,000+

Citations

1.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/32518674/

results of a pilot multicentre randomised clinical trial - PubMed

Patients demonstrated high treatment receipt; 91% of exercises performed were rated independent. Both groups demonstrated clinically important ...

A Movement Classification of Polymyalgia Rheumatica ... - PMC

SVM recorded the highest accuracy of 85% among the classifiers, while KNN had 75%, RF had 80%, and DT had the lowest accuracy of 70%.

A Movement Classification of Polymyalgia Rheumatica ...

SVM recorded the highest accuracy of 85% among the classifiers, while KNN had 75%, RF had 80%, and DT had the lowest accuracy of 70%.

Using Personalized Rehabilitation to Reduce Disease and ...

Movement pattern training is a special, personalized rehabilitation program that aims to reduce pain by improving how people move during their daily activities.

Using Personalized Rehabilitation to Reduce Disease and ...

Movement pattern training is a special, personalized rehabilitation program that aims to reduce pain by improving how people move during their ...

6.

eprints.ncl.ac.uk

eprints.ncl.ac.uk/306829

Physiotherapy for the Management of Polymyalgia ...

PMR is typically treated with glucocorticoids, but side effects are frequent and concerning to patients. 89% prescribed individualised graded exercises to ...

Outcomes of polymyalgia rheumatica in real-world practice

In a median duration of 3 weeks, 98.8% of patients achieved symptom control, with 86.4% achieving sustained remission in a median duration of 9 weeks. in 42.0% ...

(PDF) P182 Exercise and activity in polymyalgia rheumatica

The aim of this funded study was to co-create an exercise educational resource for, and with, people with PMR that would be acceptable to both patients and ...

Polymyalgia Rheumatica AND Physiotherapy

Particularly, it is assumed but not yet demonstrated that physiotherapy may support preservation of function and reduce the risk of adverse events related to GC ...

(PDF) Patient-reported Outcomes in Polymyalgia Rheumatica

Response to corticosteroid treatment was defined as 70% improvement in PMR on visual analog scale (VAS). At baseline, 77% had hip pain in ...