Social Learning Tasks for Social Cognition
(COBRA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to understand brain function, how people make decisions when they interact with others, and how brain function and behavior relate to personality traits.
Who Is on the Research Team?
Timothy A Allen, PhD
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
This study is for adults interested in how personality traits affect decision-making and social interactions. People with or without mental health or personality disorders, like narcissistic personality disorder, may be included. Specific inclusion and exclusion criteria are not listed.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants complete a battery of behavioral tasks, self-report measures, and structured clinical interviews
21-day EMA Protocol
Participants undergo a 21-day ecological momentary assessment protocol to monitor momentary interpersonal behavior
Follow-up
Participants complete additional self-report questionnaires at yearly follow-ups to assess interpersonal stress and other outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Social Learning Task Battery
Trial Overview
Researchers are using a set of online tasks to study how people learn from social situations and make decisions. Both individuals from the general public (online cohort) and those with clinical backgrounds will participate.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
The online cohort will include 718 adults ages 18-100 who will complete 1) a battery of behavioral tasks designed to assess social learning and mentalizing abilities, and 2) self-report measures assessing personality, externalizing symptoms, interpersonal functioning, and psychopathology.
The study will enroll up to 416 clinical-cohort participants, with an anticipated final eligible sample of 239 adults ages 20-60 who will complete 1) a structured clinical interview and neuropsychological assessments, 2) self-report measures assessing personality, externalizing symptoms, interpersonal functioning, and psychopathology, 3) lab-based tasks designed to assess social learning and mentalizing abilities while monitoring physiological responding with Biopac, 4) task-based fMRI, 5) 21-day ecological momentary assessment (EMA) protocol, and 6) additional self-report questionnaires at three yearly follow-ups. The investigators expect to enroll 416 participants for the start of the protocol to yield 239 final eligible participants to complete fMRI and EMA.
Additionally, 2 informants (ages 18+) for each participant will be recruited to complete self-report measures, one of whom will also enroll in EMA.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
University of Pittsburgh Medical Center
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
Emory University
Collaborator
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