Ultrasound-Guided Access for Peripheral Venous Catheterization
(TVA-2026 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether ultrasound (a technique using sound waves to create images of the body's interior) helps medical workers place a thin tube (catheter) in a vein more successfully on the first try compared to traditional methods. It involves two groups: one using ultrasound-guided peripheral vascular access and the other using standard methods like feeling and looking for veins. The trial aims to determine which method inserts the catheter more quickly and with less pain or fewer complications. Candidates for this trial include individuals who need a vein catheter as part of their medical care and can undergo either method. As an unphased trial, this study offers an opportunity to contribute to improving medical procedures for future patients.
What prior data suggests that ultrasound-guided peripheral vascular access is safe?
Research has shown that using ultrasound to guide catheter placement is generally safe. Studies indicate that ultrasound improves accuracy and reduces complications. Clinical guidelines recommend it as a safe practice. Specifically, one study found that ultrasound helped avoid more invasive procedures in 85% of difficult cases.
This technique also reduces the number of attempts needed to place a catheter successfully, resulting in less discomfort for patients. It also lowers the risks of bruising, swelling, or vein damage. These findings suggest that ultrasound guidance makes the procedure easier and safer, especially for individuals with hard-to-find veins.
Overall, existing evidence supports that ultrasound-guided vascular access is well-tolerated and effective, with fewer problems compared to traditional methods.12345Why are researchers excited about this trial?
Researchers are excited about ultrasound-guided peripheral vascular access because it offers a potential improvement over traditional methods of inserting IVs. Unlike standard techniques that rely on touch and sight to find veins, this new method uses real-time ultrasound imaging to visualize veins beneath the skin, which could lead to fewer needle sticks and quicker access. This means less discomfort for patients and a higher success rate on the first attempt, which is a big win for both patients and healthcare providers. The trial aims to find out if using ultrasound guidance can significantly reduce complications and improve overall success rates compared to conventional techniques.
What evidence suggests that this trial's techniques could be effective for peripheral venous catheterization?
This trial will compare two methods for peripheral vascular access: standard techniques and ultrasound-guided techniques. Research has shown that ultrasound helps doctors place small tubes, called catheters, into veins more effectively. Specifically, studies found that with ultrasound, doctors succeed on the first try 90% of the time, compared to just 18% with older methods. This proves especially useful for people with hard-to-find veins, often preventing the need for more complicated procedures. Using ultrasound also typically reduces the time needed to place the catheter and requires fewer attempts. Overall, ultrasound speeds up the process and increases success rates. Participants in this trial may experience these benefits if assigned to the ultrasound-guided arm.678910
Who Is on the Research Team?
Gavin C Solomon, M.D.
Principal Investigator
Truway Health, Inc.
Are You a Good Fit for This Trial?
This trial is for adults who need a peripheral IV line placed as part of their medical care. People with conditions making it unsafe or inappropriate to participate, as judged by the clinical team, will not be included.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo peripheral vascular access using either ultrasound-guided or standard techniques
Follow-up
Participants are monitored for vascular access-related complications and catheter function
What Are the Treatments Tested in This Trial?
Interventions
- Standard Peripheral Vascular Access
- Ultrasound-Guided Peripheral Vascular Access
Trial Overview
The study compares two ways of placing an IV: one uses ultrasound guidance and the other uses standard methods like feeling for veins or looking at them. Participants are randomly assigned to either group to see which method works better on the first try.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants assigned to this arm will undergo clinically indicated peripheral vascular access using real-time ultrasound guidance. The operator will use ultrasound visualization to identify an appropriate peripheral vessel and guide needle and catheter placement according to the standardized TVA-2026 vascular-access workflow. Procedural characteristics, number of cannulation attempts, time to successful access, first-attempt success, complications, rescue procedures, and other protocol-defined outcomes will be recorded.
Participants assigned to this arm will undergo clinically indicated peripheral vascular access using conventional techniques, including visual inspection, palpation, anatomical landmarks, and standard vein-selection methods without initial real-time ultrasound guidance. If vascular access cannot be successfully obtained within protocol-defined limits, clinically appropriate rescue or escalation procedures may be used and documented.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Truway Health, Inc.
Lead Sponsor
Citations
The Rationale for Ultrasound-Guided IV Access
The results of this study showed the success rate at first attempt with ultrasound at 90% vs. 18% in the group randomized to traditional cannulation [6].
The efficacy of ultrasound-guided peripheral intravenous ...
Ultrasound guided cannulation improved the first-attempt success rate compared to the traditional landmark technique in patients with DIVA.
Efficacy of Ultrasound-Guided Peripheral Intravenous ...
In one observational study, the use of ultrasound in the ED prevented the need for CVC placement in 85% of patients with difficult IV access (Au et al. 2012).
Ultrasound-guided peripheral vascular access in children
ultrasound guidance significantly increased first-attempt success (66% vs. 78%; OR 2.61) and improved overall cannulation success.(3)
Guidelines and Evidence for Ultrasound-Guided IV Access
ultrasound guidance significantly improved first-attempt success (RR 1.80; ultrasound-guided peripheral vascular cannulation demonstrated markedly higher first ...
6.
jscimedcentral.com
jscimedcentral.com/journal-article-info/Archives-of-Emergency-Medicine-and-Critical-Care/Ultrasound-Guided-Vascular-Access-Practical-Issues-(Pictorial-Essay)-11465Ultrasound Guided Vascular Access Practical Issues ...
The vein shown was found to be the only one suitable for cannulation and was easily accessible under ultrasound guidance. In such cases, ...
Guidelines and Evidence for Ultrasound-Guided IV Access
Discover how ultrasound-guided IV access is transforming care. Backed by clinical guidelines and strong evidence for safety and success.
Ultrasound Guided Peripheral IV Means Fewer CVCs
The results showed that in 85 of 100 cases (85%) USGPIVs eliminated the need for CVC placement in patients with problematic IV access. These patients also had ...
A Review of Pediatric Ultrasound-Guided Peripheral ...
This article reviews the current literature on pediatric ultrasound-guided peripheral vascular access methods and demonstrates the suitability of point-of-care ...
Guidelines for Performing Ultrasound-Guided Vascular ...
Ultrasound (US) use is recommended as a safety practice to improve successful vessel cannulation and minimize complications dur- ing vascular access.1 This ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.