Minimally Invasive Flap Procedure + Emdogain for Gum Disease

This trial tests a new treatment for gum disease using a minimally invasive technique. Researchers compare a standard gum cleaning method with a new approach that uses Emdogain, a special gel, and a videoscope to clean tooth roots more effectively. The trial seeks individuals with gum disease who have specific gum pocket sizes and some gum tissue loss. Participants should be generally healthy, smoke fewer than 10 cigarettes a day, and not have received antibiotics or gum treatments recently. As an unphased trial, this study allows participants to contribute to innovative research that could enhance future gum disease treatments.

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are taking medications that are known to inhibit or slow healing.

Previous studies have shown Emdogain to be safe. Research indicates that using Emdogain to treat gum disease has not resulted in reports of serious issues like allergic reactions, suggesting patients generally tolerate it well. Additionally, research shows that combining Emdogain with gentle techniques for gum disease improves results without compromising safety. Thus, past data suggest the treatment is safe for people.¹²³⁴⁵

Researchers are excited about these treatments for gum disease because they incorporate Emdogain, a special protein-based gel that can enhance tissue regeneration. Unlike traditional methods that solely focus on cleaning and smoothing the tooth roots, this approach aims to actively regenerate gum tissue and bone, potentially reversing damage caused by periodontal disease. The use of a videoscope in conjunction with Emdogain also offers improved visibility during the procedure, which can lead to more precise treatment and better outcomes. This innovative combination could offer a more effective and less invasive solution for patients suffering from gum disease.

Studies have shown that Emdogain, a special gel, may help regrow tissue supporting teeth lost due to gum disease. Research indicates a success rate of 30.9% at 6 months and 42.6% after about 10 years. This trial will compare two approaches: one group will receive minimally invasive periodontal therapy with Emdogain, while the control group will undergo standard root scaling and planing without it. Emdogain is used alongside procedures to clean and smooth the tooth's root, aiming to improve gum health and promote tissue regrowth. While promising, more studies are needed to fully understand its benefits.⁶⁷⁸⁹¹⁰