BioXclude™ for Gum Disease

This trial explores a new treatment for gum disease using a special membrane called BioXclude™. The study compares the effects of deep cleaning alone to deep cleaning combined with this membrane to determine if it leads to better gum health outcomes. Individuals with moderate to severe gum disease, affecting at least four teeth, might be suitable candidates. The goal is to assess whether adding the membrane can reduce gum pocket depth and improve attachment to the teeth. As an unphased trial, this study allows patients to contribute to innovative research that could enhance future gum disease treatments.

The trial requires that you have not been on chronic therapy with medications that could affect periodontal status or healing within 1 month prior to enrollment. If you are on such medications, you may need to stop taking them before joining the trial.

Research shows that the BioXclude™ treatment, which uses a special membrane made from human tissue, is under study for its safety in treating gum disease. Previous patients have generally tolerated this membrane well, experiencing few problems or side effects during treatment.

Studies have found that the growth factors in the BioXclude membrane can aid gum healing by encouraging cell growth and blood vessel formation. This is promising because it can improve gum health without significant risks. Additionally, comparisons with other treatments, like collagen dressings, have found BioXclude to be safe.

Researchers are excited about BioXclude™ for treating gum disease because it offers a unique approach compared to standard care options like scaling and root planing. Unlike traditional treatments that focus solely on cleaning, BioXclude™ involves placing a membrane in the deep pocket sites of the gums, which may help in tissue regeneration and healing. This membrane acts as a barrier, potentially promoting better and faster recovery of the gums by supporting the natural healing process. Such innovative features could lead to more effective management of gum disease, sparking interest and optimism in the dental community.

Research has shown that BioXclude™, a special membrane made from human tissue, can aid in healing gum disease. In this trial, one side of the participant's mouth will receive a deep cleaning along with the placement of a BioXclude™ membrane in the deep pocket sites. Studies indicate that this membrane contains growth factors that encourage cell growth and new blood vessel formation, enhancing gum healing. It also aids in tissue regeneration, crucial for treating gum disease. Additionally, BioXclude™ possesses antibacterial properties, helping to prevent infection and promote healthier gums. Overall, these findings support BioXclude™ as an effective option for improving dental health after deep cleaning procedures.¹²³⁶⁷