Genetic Education for Pancreatic Cancer
(REGENERATE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will test a remote approach to help people who may be at higher risk for pancreatic cancer learn about and decide whether to get genetic testing and a blood test that looks for signs of several cancers (MCED testing). The study is focused on Black, Latino/a, and Medicaid-enrolled individuals who may have had less access to cancer genetics and early detection services. About 80 participants, who reside in Massachusetts, will be assigned by chance to receive either online education alone or online education plus a phone call with a trained educator from the Pancreatic Cancer Action Network (PanCAN). After the education, participants can choose whether or not to have genetic testing and/or MCED testing. The main goal is to learn whether this approach is practical to carry out, acceptable to participants, and delivered as planned. Participants will complete 3 surveys during study participation.
Who Is on the Research Team?
Nicolette J Rodriguez, MD, MPH
Principal Investigator
Brigham and Women's Hospital
Are You a Good Fit for This Trial?
This trial is for Black, Latino/a, and Medicaid-enrolled adults living in Massachusetts who may be at higher risk for pancreatic cancer and have had less access to genetic testing or early cancer detection services.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Education
Participants receive either online education alone or online education plus a phone call with a trained educator about genetic testing and MCED testing.
Decision-making and Testing
Participants decide whether to undergo genetic testing and/or MCED testing. Testing is facilitated by the study team.
Follow-up
Participants are monitored for safety and effectiveness after testing, including follow-up surveys and potential diagnostic workup for positive results.
What Are the Treatments Tested in This Trial?
Interventions
- Online educational materials
- Telephone education session
Trial Overview
The study compares two ways of providing education about genetic and blood tests for cancer: one group gets online materials only, while the other also receives a phone session with an educator. Participants are randomly assigned to each group.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants will receive information about genetic testing and MCED testing through a telephone education session, in addition to receiving emailed links to online educational materials from the testing company.
Participants will be emailed links to online educational materials from the testing company
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor
Pancreatic Cancer Action Network
Collaborator
Exact Science Corporation
Collaborator
Dana-Farber Cancer Institute
Collaborator
Winn Career Development Award
Collaborator
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