Contrast-Enhanced Ultrasound for Pancreatic Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This pilot study is testing whether a special type of ultrasound called contrast-enhanced ultrasound (CEUS) can help detect if pancreatic cancer has come back after surgery.
People may be eligible to participate if they had surgery to remove pancreatic ductal adenocarcinoma (PDAC) from the head or body of the pancreas and are currently being monitored for cancer recurrence using CT scans.
The study plans to enroll 10 participants: 5 people whose cancer has returned and 5 people whose cancer has not returned, based on their standard medical imaging results. Participants will not be randomly assigned to groups.
Researchers will use a Logiq E10 ultrasound machine with CEUS technology to perform an ultrasound examination of the area where the surgery was performed. The goal is to determine whether CEUS can be a practical and useful tool for identifying local pancreatic cancer recurrence.
Who Is on the Research Team?
Priscilla Machado, MD, FAIUM
Principal Investigator
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Are You a Good Fit for This Trial?
This trial is for people who had surgery to remove pancreatic cancer from the head or body of the pancreas and are now being monitored for possible cancer return with CT scans.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Contrast-Enhanced Ultrasound
- Lumason
Trial Overview
The study is testing if a special ultrasound using Lumason contrast (CEUS) can help spot if pancreatic cancer has come back after surgery. Ten participants will get this scan, grouped by whether their cancer has returned or not.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants who have undergone surgical resection for pancreatic ductal adenocarcinoma and are undergoing standard of care CT surveillance will receive one contrast-enhanced ultrasound (CEUS) examination following intravenous administration of Lumason to evaluate the surgical site for local disease recurrence.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Thomas Jefferson University
Lead Sponsor
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