Knee Immobilization for Postoperative Pain

(REST-Knee Trial)

This trial explores whether wearing a knee extension brace for 72 hours after knee replacement surgery can reduce pain and improve home recovery. It compares two groups: one using the knee brace and the other following usual care with early movement. The goal is to determine if the brace can ease and lessen the pain of recovery. Individuals undergoing their first knee replacement due to arthritis might be suitable candidates. The trial will also aid in planning a larger future study to enhance knee surgery recovery. As an unphased trial, it offers patients the chance to contribute to research that could improve recovery experiences for future knee surgery patients.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that wearing a knee extension brace immediately after knee replacement surgery can help manage pain. One study found that patients who wore a brace for 72 hours experienced less pain and better recovery. These braces are generally well-tolerated, with most patients not experiencing serious side effects.

Another study on similar braces found they can improve knee function and reduce swelling. While braces are usually safe, some people might feel discomfort or stiffness. No major safety issues have been reported, indicating that using a brace is a safe option for many people recovering from knee surgery.

Researchers are excited about the knee extension brace technique for managing postoperative pain after total knee arthroplasty because it offers a novel approach compared to the standard care of early mobilization. Unlike traditional methods that encourage immediate movement, this technique involves keeping the knee immobilized in full extension for 72 hours using a Zimmer-type knee brace. This method could potentially reduce pain and improve recovery by minimizing movement immediately after surgery, which may be beneficial for some patients. By exploring this technique, researchers hope to find out if immobilization can enhance recovery outcomes and provide a new postoperative care option for patients undergoing knee replacement surgery.

In this trial, participants in the Extension Brace Group will immobilize the operated knee in full extension using a Zimmer-type knee brace for 72 hours following primary total knee arthroplasty. Research has shown that wearing a knee brace for this duration after knee surgery can reduce pain and speed up recovery. One study found that these braces, often worn for weeks or months after surgery, relieve pain and limit knee movement, aiding healing. Other research suggests that even short-term brace use can lead to better knee function and less pain. Patients using similar braces reported improved movement and easier mobility. Overall, evidence supports that knee braces effectively manage pain and improve recovery after knee surgery. Meanwhile, participants in the Standard Care Group will receive standard postoperative care, which includes early mobilization without movement restriction and supervised physiotherapy according to usual clinical practice.²⁵⁶⁷⁸