140 Participants NeededMy employer runs this trial

Corticosteroid Injection for Knee Arthritis

(Medial OA CSI Trial)

Recruiting at 4 trial locations
MJ
Overseen ByMalik J Scott, B.A.
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Chicago
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee. Participants will:

1. Be randomly divided into getting their steroid injection on the inside or outside of their knee.

2. Answer a pain survey before their injection as well as over the phone 2 weeks, 6 weeks, and 12 weeks after their injection.

Who Is on the Research Team?

SJ

Sara JS Wallace, M.D./M.P.H.

Principal Investigator

The University of Chicago Medical Center

BP

Brandon Pardi, M.D.

Principal Investigator

AdventHealth

Are You a Good Fit for This Trial?

This trial is for adults with knee osteoarthritis, especially those with pain on the inside of their knee. People who have other major health issues or conditions affecting study participation may not be eligible.

Inclusion Criteria

Able to provide informed consent
Able to complete phone, email, or MyChart follow-ups in English
I have knee osteoarthritis mainly affecting the inner side of my knee.
See 3 more

Exclusion Criteria

Inability to complete follow-up assessments
Other clinician-determined contraindication to CSI
I am scheduled for knee surgery within the next 12 weeks.
See 4 more

What Are the Treatments Tested in This Trial?

Interventions

  • Anterolateral Injection
  • Anteromedial Injection

Trial Overview

The study compares two ways of giving a steroid injection—either on the inside (anteromedial) or outside (anterolateral) of the knee—to see which works better for reducing pain and improving function. Participants are randomly assigned to one group.

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: AnterolateralActive Control1 Intervention
Group II: AnteromedialActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Chicago

Lead Sponsor

Trials
1,086
Recruited
844,000+

AdventHealth

Collaborator

Trials
118
Recruited
31,800+