Shockwave Therapy for Knee Arthritis

CA
Overseen ByCameron A Hall, DC, PhD
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Pulse Wave USA
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial compares focused shockwave therapy to standard physical rehab for individuals with knee osteoarthritis, a condition affecting the knee joint. The researchers aim to determine if this new treatment can improve knee function and reduce pain without requiring rehab exercises. Participants will be divided into two groups: one will receive focused shockwave therapy, while the other will undergo regular physical rehab. Ideal candidates have been diagnosed with grade I-III knee osteoarthritis, indicating the knee joint is affected but not severely damaged. As an unphased trial, this study provides patients the chance to explore innovative treatments that could enhance their quality of life.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that focused shockwave therapy is safe for knee osteoarthritis?

Previous studies have shown that focused shockwave therapy is safe for treating knee osteoarthritis. Research indicates that this therapy can significantly reduce pain and improve knee function. Importantly, the studies found no major side effects, suggesting the treatment is generally well-tolerated. Some minor, temporary discomfort may occur during or after the treatment, but serious issues are rare. Overall, the evidence supports the safety of focused shockwave therapy for knee arthritis.12345

Why are researchers excited about this trial?

Most treatments for knee arthritis, like pain medications, physical therapy, or steroid injections, focus on managing symptoms. However, focused shockwave therapy is unique because it uses sound waves to target the affected area, potentially stimulating healing and reducing pain without drugs or invasive procedures. Researchers are excited about this technique because it could offer a non-invasive alternative with fewer side effects and possibly longer-lasting relief compared to traditional methods.

What evidence suggests that focused shockwave therapy is effective for knee arthritis?

Research has shown that focused shockwave therapy, which participants in this trial may receive, can help reduce pain and improve movement in people with knee osteoarthritis (OA). In one study, individuals who received shockwave therapy reported a 45% drop in pain, while those in a comparison group experienced an 18% reduction. Another study found that focused shockwave therapy was more effective than radial shockwave therapy for reducing pain and improving physical function. Reviews of multiple studies also suggest that using higher energy levels and more shock treatments can lead to better results. Overall, focused shockwave therapy appears to be a promising option for relieving knee OA symptoms. Participants in this trial will be assigned to either the Focused Shockwave Therapy Group or the Physical Rehab Group to compare these approaches.13467

Who Is on the Research Team?

CA

Cameron A Hall, DC, PhD

Principal Investigator

Pulse Wave USA

Are You a Good Fit for This Trial?

This trial is for people diagnosed with mild to moderate knee osteoarthritis (grade I-III) in one or both knees. Participants must not have more severe forms of the disease or other major health issues affecting their knees.

Inclusion Criteria

I have been diagnosed with mild to moderate knee osteoarthritis.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either focused shockwave therapy or standard physical rehabilitation

8 to 12 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Focused Shockwave Therapy

Trial Overview

The study compares two treatments: focused shockwave therapy alone versus standard physical rehabilitation, to see which works better for knee osteoarthritis. Participants are randomly assigned to one group and do not know which treatment they receive.

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: Physical Rehab GroupActive Control1 Intervention
Group II: Focused Shockwave Therapy GroupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Pulse Wave USA

Lead Sponsor

Citations

The Efficacy of Focused Extracorporeal Shockwave Therapy ...

We found that focused shockwave use can appropriately rehabilitate the knee function and reduce knee osteoarthritis pain. Further studies to ...

Comparative Effectiveness of Focused Extracorporeal versus ...

Our results showed that f-ESWT was more effective than r-ESWT in improving pain and physical function in patients with knee osteoarthritis.

A systematic review of the use of shockwave therapy for ...

Conclusions. This review demonstrated that ESWT was effective for knee OA. Higher energy and more shock numbers could obtain better efficacy. ESWT could be used ...

Effectiveness of extracorporeal shock wave therapy on ...

The results following the four weeks of study protocol demonstrated that ESWT with CPT and CPT alone were effective in improving functional ...

Shock Wave Treatment in Patients With Knee Osteoarthritis

Before starting treatment, patients will be randomized into treatment groups: shockwave treatment combined with knee strengthening exercises (intervention group) ...

The efficacy and safety of extracorporeal shockwave ...

The combined data showed that ESWT was associated with a significant reduction of pain score within 12 weeks after treatment. Functional recovery of knee joint ...

The Dose-Related Effects of Extracorporeal Shock Wave ...

In this study, medium-energy group (group M) showed greater improvement in regard to relieving pain and restoring functional outcome than the low-energy group ...