Nerve Blocks for Hip Osteoarthritis

(PENG Trial)

This trial aims to determine which nerve block better manages pain after hip replacement surgery: the fascia iliaca nerve block or the pericapsular nerve block. Both methods target specific nerves to reduce pain in the hip area. The trial seeks participants planning to undergo hip replacement using the anterior (front) approach and who have not regularly used opioids (strong pain medications) before. As a Phase 4 trial, the treatment is already FDA-approved and proven effective, allowing researchers to understand how it benefits more patients.

The trial does not specify if you need to stop taking your current medications, but you must not be taking opioids regularly before joining. If you are on opioids, you may need to stop them to participate.

Research shows that both the fascia iliaca nerve block and the pericapsular nerve block are generally safe for managing pain after hip surgery.

For the fascia iliaca nerve block, studies have found it effectively reduces pain and the need for pain medication like morphine after surgery. Patients using this block experienced less pain and required fewer pain-relieving drugs soon after their operation.

Regarding the pericapsular nerve block, research suggests it also effectively reduces pain and decreases the use of pain medications after surgery. This block targets specific nerves near the hip, aiding in pain management and improving recovery.

Researchers are excited about nerve blocks for hip osteoarthritis because they offer a unique approach compared to traditional pain management options like oral medications or injections. Fascia Iliaca Nerve Block specifically targets the space between the iliacus muscle and fascia, directly affecting the femoral and lateral femoral cutaneous nerves. Meanwhile, the Pericapsular Nerve Block focuses on the anterior hip capsule, blocking the articular branches of the femoral and accessory obturator nerves. These targeted techniques aim to provide more precise pain relief, potentially reducing side effects associated with systemic treatments. This precision in targeting could mean faster and more effective relief for patients suffering from hip osteoarthritis.

This trial will compare the effectiveness of two nerve block treatments for hip osteoarthritis: the Fascia Iliaca Nerve Block and the Pericapsular Nerve Block. Studies have shown that fascia iliaca nerve blocks effectively reduce pain and the need for opioids after hip surgeries, providing good pain relief for up to 24 hours. Research indicates that patients using fascia iliaca blocks often require less morphine and experience shorter hospital stays.