ED-LINC for Opioid Use Disorder

(ED-LINC2 Trial)

This trial tests a new healthcare approach called ED-LINC (Emergency Department Longitudinal Integrated Care) to assist individuals with opioid use disorder. The goal is to determine if this method reduces illegal opioid use, encourages adherence to treatment medications, and decreases emergency room visits. Participants will receive either usual care or the ED-LINC intervention, which includes overdose education and ongoing support. Individuals who have struggled with opioid use for some time and can be contacted by phone may be suitable for this trial. As an unphased study, this trial provides a unique opportunity to contribute to innovative care strategies for opioid use disorder.

The trial information does not specify whether you need to stop taking your current medications. However, if you are receiving chronic opioid therapy, you are not eligible to participate.

Research has shown that the ED-LINC program, designed to manage opioid use disorder, was tested in a small study. In this trial, researchers randomly assigned 40 patients to either the ED-LINC program or the usual care. The results indicated that patients in the ED-LINC group experienced no more side effects than those in the usual care group. Additionally, the study successfully followed over 80% of participants for up to 6 months. This suggests that ED-LINC is safe and well-tolerated by patients, with no major safety issues reported.¹²³⁴⁵

Researchers are excited about the ED-LINC intervention for opioid use disorder because it offers a comprehensive approach that goes beyond typical treatments like medication-assisted therapies (e.g., methadone, buprenorphine). Unlike standard care, ED-LINC includes personalized overdose education and a brief bedside intervention aimed at boosting motivation to seek outpatient care. It also employs a patient-centered decision support tool for medication-assisted treatment, along with proactive and ongoing care management. This holistic approach is designed to not only address opioid use but also tackle related health issues, potentially leading to more sustained recovery outcomes.

Research has shown that the ED-LINC program is designed to assist people with opioid addiction, starting in the emergency room. In this trial, participants will receive either the ED-LINC intervention or usual care. An initial study found that patients who received ED-LINC did not use heroin less than those who received regular care. However, the program includes valuable features such as education on preventing overdoses and motivational talks to encourage further treatment. It also provides a plan for ongoing care, which is crucial for those dealing with opioid issues. While early results show limited effects on drug use, the program’s comprehensive support system could enhance treatment involvement and care.¹²³⁶⁷