RIMO for Opioid Use Disorder
(RIMO Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines a new method to support individuals recovering from an opioid overdose. It aims to determine if the Recovery Initiation and Management after Overdose (RIMO) program, which offers personalized recovery support, is more effective in facilitating treatment entry than the standard referral process. Participants will either receive RIMO support or information about available treatment options. The trial is open to individuals in Chicago who experienced an overdose reversed by naloxone in the past week and have not recently been in treatment. As an unphased trial, it provides participants the chance to contribute to innovative recovery strategies that could influence future care.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the research staff when you are contacted.
What prior data suggests that the RIMO intervention is safe for individuals with opioid use disorder?
Research has shown that the Recovery Initiation and Management after Overdose (RIMO) program helps individuals access necessary treatment following an overdose. In past studies, participants using the RIMO method were more likely to receive treatment than those who did not. Reports of side effects or negative experiences with RIMO are few, as it emphasizes meetings and support rather than medication.
In the RIMO program, participants collaborate with trained specialists who employ motivational interviewing. This technique helps individuals recognize the benefits of treatment and overcome obstacles like finding childcare or transportation. As a supportive, non-medical approach, RIMO is generally considered safe for individuals to try.12345Why are researchers excited about this trial?
Researchers are excited about the RIMO approach for opioid use disorder because it combines motivational interviewing with practical support to overcome barriers to treatment. Unlike traditional methods, such as Medication-Assisted Treatment (MAT) alone, RIMO actively engages participants by addressing their personal obstacles like childcare and transportation. This personalized and supportive strategy not only motivates individuals to initiate recovery after an overdose but also helps them stay committed to long-term change, something standard treatments may not fully address.
What evidence suggests that the RIMO intervention is effective for opioid use disorder?
Research has shown that the Recovery Initiation and Management after Overdose (RIMO) program, which participants in this trial may receive, effectively helps people begin treatment for opioid addiction. One study found that individuals in the RIMO program were almost eight times more likely to receive any form of treatment for opioid use. They were also over twenty times more likely to receive medication-assisted treatment (MAT), which uses medicines to help manage addiction. This indicates that RIMO significantly increases the chances of obtaining necessary help to manage opioid use after an overdose.12356
Who Is on the Research Team?
Christine E Grella, Ph.D.
Principal Investigator
Chestnut Health Systems
Are You a Good Fit for This Trial?
This trial is for adults in Chicago who've had an opioid overdose reversed with naloxone by first responders in the past week, are not currently in treatment, and have a positive screen for Opioid Use Disorder. They must be over 18, able to consent, and speak English.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomly assigned to either the RIMO intervention or passive referral control group. RIMO participants receive motivational interviewing and support for MAT engagement.
Follow-up
Participants are monitored for safety and effectiveness after treatment, including assessments of opioid use, health care utilization, and mental health.
What Are the Treatments Tested in This Trial?
Interventions
- Passive Referral to Treatment Control
- Recovery Initiation and Management after Overdose (RIMO)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Chestnut Health Systems
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Collaborator