Beetroot Juice for High Blood Pressure

(BEET-DOWN Trial)

MG
Overseen ByMoney Ghimire, M.S
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Virginia

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise alone.

Who Is on the Research Team?

JA

Jason Allen

Principal Investigator

University of Virginia

SA

Siddhartha Angadi

Principal Investigator

University of Virginia

Are You a Good Fit for This Trial?

This trial is for adults who have obesity or abdominal obesity and high blood pressure. Participants should not have any major health issues that would prevent them from safely taking part in exercise or consuming beetroot juice.

Inclusion Criteria

Sedentary (<150 minutes of moderate intensity aerobic exercise per week, or not engaged in a regular exercise program at all)
Willingness and ability to comply with scheduled visits and study procedures
Resting systolic BP ≥ 120 mmHg
See 6 more

Exclusion Criteria

I have oral cancer or a serious mouth disease.
Current medical condition that prohibits exercising at high intensities
Body mass index ≤ 29.9 Kg/m2
See 11 more

What Are the Treatments Tested in This Trial?

Interventions

  • Beetroot Juice

Trial Overview

The study tests if drinking beetroot juice (which contains inorganic nitrate) before exercise lowers blood pressure more than exercise alone, using four groups: with/without beetroot juice and with/without exercise. Some get a placebo instead of real beetroot juice.

How Is the Trial Designed?

4

Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: AExperimental Treatment1 Intervention
Group II: BActive Control1 Intervention
Group III: CPlacebo Group1 Intervention
Group IV: DPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Virginia

Lead Sponsor

Trials
802
Recruited
1,342,000+