500 Participants NeededMy employer runs this trial

MiWeigh Program for Obesity

SS
Overseen ByShelley Stoll
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program called MiWeigh to determine if it aids in weight loss more effectively than receiving weight loss advice alone. Researchers aim to identify which components of MiWeigh are effective and how it might help prevent or manage obesity-related issues such as Type 2 Diabetes or high blood pressure. Individuals with a BMI of 30 or higher, along with conditions like Type 2 Diabetes, prediabetes, or high cholesterol, who are interested in losing weight, may be suitable candidates. Participants must be comfortable using electronic health tools and report their weight weekly if assigned to the program. As an unphased trial, this study provides a unique opportunity to contribute to innovative weight management strategies that could benefit many people.

Do I need to stop taking my current medications for the MiWeigh Program trial?

The trial does not specify if you need to stop taking your current medications. However, if you are taking an anti-obesity medication, you cannot participate in the trial.

Is there any evidence suggesting that the MiWeigh program is safe?

Research shows that most people find the MiWeigh program easy to manage. A study on a similar weight loss program produced good results without major side effects, suggesting participants experienced no significant issues.

The MiWeigh program might also include personalized check-ups, enhancing safety for each individual. Available data shows no evidence of serious safety problems. However, as with any program, individual experiences may vary.12345

Why are researchers excited about this trial?

Unlike other treatments for obesity that often involve medications or surgical interventions, the MiWeigh program focuses on a comprehensive lifestyle approach. Researchers are excited about MiWeigh because it integrates personalized coaching, technology-driven tracking, and community support to help individuals make sustainable lifestyle changes. This holistic approach not only aims to reduce weight but also to improve overall health and well-being, making it a potentially transformative option for individuals struggling with obesity.

What evidence suggests that the MiWeigh program is effective for obesity?

Research has shown that the MiWeigh program, which participants in this trial may receive, can aid in weight loss. One study found that people in the MiWeigh program lost significant weight, with some losing more than 10% of their body weight after a year. Another study reported an average weight loss of 15.3% in just four months. This trial will compare the MiWeigh program to Enhanced Usual Care, which provides information about weight loss. The program's structured plan appears crucial for these outcomes.12678

Who Is on the Research Team?

DG

Dina Griauzde, MD, MSc

Principal Investigator

University of Michigan

Are You a Good Fit for This Trial?

This trial is for English-speaking adults with a BMI of 30 or higher who are interested in losing weight and have conditions like type 2 diabetes, prediabetes, high cholesterol, high blood pressure, PCOS, sleep apnea, or fatty liver disease. Participants must be willing to complete study assessments.

Inclusion Criteria

* Speaks English
I am interested in losing weight.
* Willingness to complete assessments per study protocol
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in the MiWeigh program or receive enhanced usual care to assess weight loss effectiveness

12 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • MiWeigh

Trial Overview

The study compares the MiWeigh program—a structured weight loss support system—to enhanced usual care (EUC), where participants receive information about weight loss strategies. The goal is to see which approach helps people lose more weight.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: MiWeighExperimental Treatment1 Intervention
Group II: Enhanced Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Michigan

Lead Sponsor

Trials
1,891
Recruited
6,458,000+

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

Trials
2,513
Recruited
4,366,000+

Citations

The WEIGH Study: Weighing to Improve and Gain Health

While daily self-weighing has been shown to be effective for weight loss in observational research, there is limited experimental evidence testing this ...

Michigan Weight Navigation Program (MiWeigh) Study

Percentage of participants achieving ≥ 10% weight loss at 12 months. Baseline, 12 months. Based on kilograms. ; Change in waist circumference from baseline to 12 ...

MiWeigh Program for Weight Loss and Obesity-Related ...

The primary outcome measured is the change in body weight in kilograms from the start of the study to 12 months later. This will help determine the ...

Efficacy of a Commercial Weight Management Program ...

At 12 months, retention rates were 88.8% (166 of 187) for the commercial weight management program group and 95.7% (178 of 186) for the DIY ...

MiWeigh Program for Obesity

The main purpose of this study is to determine whether people who participate in MiWeigh lose more weight than people who receive information about weight ...

Real-World Effectiveness of a Medically Supervised Weight ...

In those with 5-year follow-up, weight loss between 5.0 and 9.9% below baseline occurred in 16.3% (SE = 0.004, 95% CI = 15.3% – 17.2%) and weight loss of 10.0% ...

Long-term effects of 12-month integrated weight-loss ...

The aim of our study was to assess long-term effects of the 12-month integrated weight-loss programme in children with excess body weight.

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miweigh.org

miweigh.org/other

Other Programs and Resources - MiWeigh

The program may include a comprehensive history and physical exam, genetic screening if indicated, and laboratory assessments to guide individualized treatment ...