Postbiotic for Obesity

This trial tests an oral postbiotic supplement to assess its effects on metabolic health in overweight adults. Participants will take either a postbiotic supplement or a placebo (a pill with no active ingredients) daily. It suits adults with a body mass index (BMI) between 25 and 40 who do not smoke or have major health issues like heart or liver problems. Participants must maintain their usual diet and exercise habits and avoid other supplements.

As an unphased trial, this study allows participants to contribute to groundbreaking research in metabolic health.

The trial information does not specify if you need to stop taking your current medications. However, you must avoid other probiotic and postbiotic supplements during the study.

Research shows that postbiotics are usually safe for people to use. Studies suggest that postbiotics can help with metabolism and weight issues without causing major side effects. One review pointed out that postbiotics are a safe choice and can help reduce fat growth while increasing energy use. So far, these findings indicate that taking postbiotics is safe for humans, with no serious negative effects reported.¹²³⁴⁵

Unlike the standard treatments for obesity, which often include lifestyle changes, medications like orlistat, or surgical options, the postbiotic supplement under study offers a novel approach. This treatment is unique because it combines a postbiotic with a herbal blend and vitamins, taken in a simple daily capsule. Researchers are particularly excited about its potential to influence gut health and metabolism through postbiotics, which are non-living bacterial products or byproducts. This mechanism could offer a new way to support weight management by enhancing gut microbiota balance, which is a different angle from current options that primarily focus on appetite suppression or fat absorption.

This trial will compare a postbiotic supplement with a placebo to evaluate its effects on obesity. Research has shown that postbiotics might aid in obesity management. Studies suggest they can lead to an average weight loss of about 9 grams. They also appear to reduce the formation of new fat cells and increase the body's energy expenditure. Additionally, postbiotics may improve sugar metabolism by enhancing insulin sensitivity and reducing inflammation. These factors are important for managing obesity. Overall, postbiotics are considered a safe and potentially effective option for weight management.¹²⁴⁶⁷