NDPP-NextGen for Diabetes Risk Reduction

This trial tests a new online program called NDPP-NextGen, designed to help young women improve their health before and during pregnancy. It focuses on reducing the risk of developing diabetes and managing weight through virtual classes on healthy eating and exercise. Women who are overweight, planning to become pregnant within two years, and are patients at specific health centers can participate. Participants will learn lifestyle changes that may benefit both their health and their baby's health.

As an unphased trial, this study offers a unique opportunity for participants to proactively enhance their health and their future baby's health through innovative lifestyle changes.

The trial information does not specify whether you need to stop taking your current medications. However, if you are using long-acting contraceptives and plan to continue for more than a year, you may not be eligible to participate.

Research has shown that the Diabetes Prevention Program (DPP) effectively reduces the risk of developing type 2 diabetes. Studies found that participants in the DPP Lifestyle Change Program lowered their diabetes risk by 58%. This program involves lifestyle changes such as healthier eating and regular exercise.

The NDPP-NextGen is an improved version of this program, designed specifically for young women who may have children in the future. Although the NDPP-NextGen is new, many have successfully participated in the original DPP without experiencing serious side effects from the lifestyle changes it promotes.

Researchers are excited about NDPP-NextGen because it offers a unique approach to reducing diabetes risk by focusing on lifestyle changes before pregnancy. Unlike standard care options that typically address diabetes risk through medication or post-diagnosis intervention, this program emphasizes prevention through online classes led by trained Lifestyle Coaches. These classes teach women how to eat healthy, be active, and manage weight, all while providing ongoing support via video-conferencing and motivational interviewing. This proactive and personalized approach could effectively lower diabetes risk, empowering women with the tools they need to maintain a healthy lifestyle before, during, and after pregnancy.

Initial findings suggest that the National Diabetes Prevention Program (NDPP) effectively lowers the risk of diabetes. Studies have shown that participants lose an average of about 4% of their body weight, with younger adults and women losing around 2%. The program also significantly reduces the chance of developing diabetes in people with prediabetes. In this trial, participants in the Healthy Lifestyle group will engage with the NDPP-NextGen, an improved version of the program, expected to enhance maternal health and further reduce diabetes risk in women. Overall, the NDPP offers a promising way to manage weight and decrease the risk of diabetes.⁶⁷⁸⁹¹⁰