Cancer Pain 101 for Cancer Pain

(COPES Aim 3 Trial)

CF
EH
Overseen ByErin Hornsby
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Alabama at Birmingham
Must be taking: Opioids
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether a series of three short videos, called "Cancer Pain 101," can help people with advanced cancer manage their pain more effectively, especially when using opioid medications. Participants will be divided into two groups: one will watch the videos, and the other will receive a written handout about cancer pain. The study seeks individuals with advanced cancer who experience cancer-related pain and are currently using or planning to use opioids for pain relief. The goal is to determine if the videos can ease pain management with opioids and reduce the stigma around these medications. As an unphased trial, this study offers a unique opportunity to contribute to innovative approaches in pain management for cancer patients.

What prior data suggests that this behavioral intervention is safe for people with advanced cancer?

Research has shown that the Cancer Pain 101 videos offer a new method for managing cancer pain. As a behavioral treatment rather than a medication, it is generally considered safe. No reports of harmful side effects have emerged from watching these videos. Instead, the videos aim to enhance understanding and management of pain. This approach is typically well-received because it emphasizes education and self-management over new drugs or treatments.12345

Why are researchers excited about this trial?

Researchers are excited about Cancer Pain 101 because it offers a fresh, digital approach to managing cancer pain. Unlike traditional methods that rely heavily on medications, Cancer Pain 101 provides patients with educational videos on pain management and self-care techniques, all accessible through a convenient app. This empowers patients to take an active role in managing their pain, potentially reducing their dependency on medications. Additionally, the digital format allows for easy access anytime, making it a flexible and personalized resource for patients seeking to better understand and manage their pain.

What evidence suggests that this behavioral intervention could be effective for cancer pain?

Research has shown that self-management techniques can significantly reduce cancer pain for many patients. In this trial, participants in the Cancer Pain 101 Intervention group will access videos designed to lower pain levels and improve pain management. Early results suggest that patients receive these videos positively. In one study, participants who watched similar educational videos reported less pain after two weeks. Such strategies often help individuals feel more in control of their pain, leading to better pain management and an improved quality of life. Overall, educational and psychological tools appear promising for relieving cancer pain.678910

Who Is on the Research Team?

HW

Hailey W Bulls, PhD

Principal Investigator

University of Alabama at Birmingham

Are You a Good Fit for This Trial?

This trial is for adults with advanced cancer who are experiencing pain and want help managing it. Participants should be able to watch videos or read handouts, complete questionnaires, and receive care at the University of Alabama at Birmingham.

Inclusion Criteria

Speaks English
I am currently taking or planning to start opioids for my cancer pain.
I am 18 years old or older.
See 2 more

Exclusion Criteria

Prior participation in aspects of this study (i.e., K08 Aims 1 and 2)
I am unable to give informed consent for my treatment.
Observable psychiatric disorders that would interfere with study participation (e.g., dementia, psychosis)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive either a digital video intervention or a written handout about cancer pain

4 weeks
Digital access to videos or receipt of handout

Follow-up

Participants are monitored for changes in pain management and opioid stigma through questionnaires

4 weeks
Completion of follow-up questionnaires

What Are the Treatments Tested in This Trial?

Interventions

  • Cancer Pain 101

Trial Overview

The study is testing whether a set of three short educational videos can help people with advanced cancer better manage their pain and reduce stigma around using opioid medications, compared to receiving written information only.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Cancer Pain 101 InterventionExperimental Treatment1 Intervention
Group II: Educational ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Alabama at Birmingham

Lead Sponsor

Trials
1,677
Recruited
2,458,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Citations

Interventions to support self-management in cancer pain - PMC

Guideline-based treatment can significantly control cancer pain and it is estimated that cancer pain may be significantly relieved in between 70% and 90% of the ...

Initial Feasibility and Acceptability of Cancer Pain 101: An ...

We developed a 90-min, single-session, telehealth, interdisciplinary intervention that combines cancer-specific medical education and behavioral ...

Cancer pain self-management interventions in adults

This study thoroughly examined the provision of cancer pain self-management by healthcare professionals and identified four intervention types from 23 studies.

Effect of Pain Coping Skills Training on ...

Cognitive-behavioral pain intervention protocols reduce pain severity and improve self-efficacy for pain management. These interventions ...

Cancer Pain Management: A Narrative Review of Current ...

Some data indicate that the presence of poorly relieved pain may decrease survival rates in cancer [5,6]. Recent developments in oncology, which ...

Cancer Pain 101: A Digital, Asynchronous... | Clinical Trial

The videos cover cancer pain, pain medications, and pain self-management skills, and will be available for four weeks.

Navigating Opioids and Other Strategies for Managing ...

Several studies indicate that topical pain treatments such as lidocaine can be an effective pain treatment for many patients with cancer.

8.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/31056379/

Pharmacologic Management of Cancer Pain

Medications are the mainstay of cancer pain management. Evidence exists for multimodal use of opioids, non-opioids, and co-analgesics to optimally manage ...

Opioid Self-management Practices and Potential Safety Risks ...

These reported practices included self-stopping and resuming opioids, increasing duration between prescribed opioid doses, using a concoction of ...

Opioid Sparing Pain Management Strategies for Cancer ...

Non-opioid analgesics Acetaminophen Oral NSAIDS (with caution) Topical NSAID (diclofenac gel or patch) Buprenorphine transdermal has been suggested to be safe ...