Exercise for Cancer
(PAC ICare Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Building on previous research that shows the benefits of exercise, this study aims to find out how best to implement exercise in real-world settings. The study will assess the feasibility and acceptability of an embedding an automated referral tool and an exercise professional into standard cancer care impacts clinician referral and patient uptake of exercise programming. The study will assess how effective the exercise program is at improving patients' physical health, quality of life, symptom management, and overall wellbeing during different stages of their cancer journey (e.g., before treatment, on treatment, after treatment).
Who Is on the Research Team?
Melanie Keats, PhD
Principal Investigator
Dalhousie University and Nova Scotia Health
Are You a Good Fit for This Trial?
This trial is for people diagnosed with cancer at any stage—before, during, or after treatment—who are able to participate in an exercise program. There are no detailed exclusions listed.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-treatment (Prehabilitation)
Participants preparing for surgery engage in a prehabilitation intervention to optimize physical functioning prior to surgery.
Active Treatment
Participants receiving adjuvant therapy or post-surgery engage in a 12-week exercise intervention.
Post-Treatment (Rehabilitation/Early Survivorship)
Participants who have completed treatment engage in a progressively tapered exercise program.
Follow-up
Participants are monitored for safety and effectiveness after treatment.
What Are the Treatments Tested in This Trial?
Interventions
- Exercise
Trial Overview
The study tests whether adding automatic referrals and access to an exercise professional within standard cancer care helps more patients join and benefit from exercise programs. It looks at effects on physical health, symptoms, and quality of life.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Participants preparing for surgery, a minimum 3-week prehabilitation intervention will be implemented to optimize physical functioning prior to the surgical procedure. Supervised exercise sessions will be delivered 2-3 times per week throughout the pre-surgical intervention, with participants encouraged to engage in 30 minutes of walking on non-supervised days. Individuals undergoing neoadjuvant therapy will continue participating in the exercise program up to the date of surgery, up to a maximum duration of 12 weeks of supervised exercise programming.
Participants who have completed treatment will engage in a progressively tapered exercise program. This program will involve supervised sessions 3 times per week during the initial four weeks, followed by 2 sessions per week for the subsequent four weeks, and 1 session per week for the remaining 12 weeks. Participants will be encouraged to walk 30 minutes/day on non-supervised exercise days. The final four weeks will emphasize the transition toward independent exercise participation, incorporating self-monitoring strategies and mid-month (week 14) check-in to address any emerging concerns and support appropriate adjustments to the program.
Participants receiving adjuvant therapy who are not scheduled for surgery, as well as those who have recovered from surgery, will be enrolled in a 12-week exercise intervention. Supervised sessions will be delivered 2 times per week and an independent walking program of 30 minutes/day on non-supervised exercise days will be encouraged.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Melanie Keats
Lead Sponsor
Queen Elizabeth II Health Sciences Centre
Collaborator
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