Postoperative Guidelines for Cancer Surgery

AN
Overseen ByAmber N Taylor (Clinical Research Regulatory Coordinator I), BS, MA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Alabama at Birmingham
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial focuses on improving recovery after high-risk abdominal cancer surgery. Researchers are testing new guidelines, known as the Algorithmic Guideline for Functional Recovery following Cancer Surgery, to assist surgeons in making better decisions for patient recovery. The trial aims to enhance patients' post-surgery recovery. Surgeons performing abdominal cancer surgeries at the study institution are the main participants. As an unphased trial, this study allows patients to contribute to innovative recovery strategies that could improve surgical outcomes.

What prior data suggests that this guideline is safe for postoperative use?

Research has shown that following recovery guidelines after cancer surgery can help patients feel better. Studies have found that these guidelines reduce common side effects like pain and nausea. They also enable patients to resume normal activities more quickly and improve overall health.

For example, one study found significant health improvements in patients within six months after surgery, indicating that the guidelines are both effective and easy to follow. Another study showed that these recovery plans help the body resume normal functions, such as bowel movements.

The evidence suggests that using a structured recovery plan is generally safe and can enhance quality of life after surgery. Although specific numbers on negative effects are not available, the consistent improvement in recovery suggests that any negative effects are likely minimal.12345

Why are researchers excited about this trial?

Researchers are excited about the Algorithmic Guideline for Functional Recovery following Cancer Surgery because it introduces a new way to support postoperative care. Unlike traditional postoperative protocols that rely on general guidelines, this algorithm offers personalized decision support for surgeons, aimed at enhancing a patient’s functional recovery. By tailoring postoperative care to individual needs, this approach has the potential to improve recovery outcomes and could lead to more efficient use of healthcare resources.

What evidence suggests that this guideline is effective for improving functional recovery after cancer surgery?

Research has shown that following specific guidelines after cancer surgery can greatly aid recovery. One study demonstrated significant health improvements in patients within six months post-surgery, with health scores rising from 74.92 to 86.53. Additionally, Enhanced Recovery After Surgery (ERAS) methods have proven effective in reducing pain, speeding digestive recovery, and decreasing complications. This trial will evaluate the effectiveness of a postoperative decision support guideline provided to surgeons, aiming to enhance recovery after major abdominal surgeries for cancer. These findings suggest that such guidelines can effectively support better recovery in these cases.23678

Who Is on the Research Team?

KE

Kimberly E Kopecky, MD,MSCI

Principal Investigator

University of Alabama at Birmingham

Are You a Good Fit for This Trial?

This trial is for surgeons at the study hospital who perform abdominal cancer surgeries. Surgeons who do not operate on abdominal cancers or work outside this hospital cannot participate.

Inclusion Criteria

Surgeons who perform abdominal surgery for cancer at the study institution

Exclusion Criteria

I do not perform abdominal cancer surgeries.
Surgeons who are external to the study institution

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Guideline Development

Development of algorithmic guidelines focused on proactive support of surgical recovery

2 months

Implementation

Implementation of the algorithmic guidelines into postoperative care workflows

6 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Algorithmic Guideline for Functional Recovery following Cancer Surgery

Trial Overview

The study is testing new step-by-step guidelines to help improve patient recovery after high-risk abdominal cancer surgery. The goal is to see if these guidelines can lead to better functional outcomes.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: SurgeonsExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Alabama at Birmingham

Lead Sponsor

Trials
1,677
Recruited
2,458,000+

Citations

GOSAFE - Geriatric Oncology Surgical Assessment and ...

Abstract. Objective. Older patients with cancer value functional outcomes as much as survival, but surgical studies lack functional recovery (FR) data.

Enhanced recovery after surgery pathways and postoperative ...

ERAS reduced the time to first exhaustion and defecation, lowered pain scores, decreased postoperative complications, and improved quality of life

Enhanced Recovery After Colon and Rectal Surgery from ...

Outcomes of interest include alleviating nausea and pain, achieving early return of bowel function, and decreasing rates of wound infection

Study Details | NCT07720089 | Development and ...

This is a pilot feasibility study to test the clinical use of a novel algorithmic guideline to support patient functional recovery following cancer surgery.

Quality of Life and Functional Outcomes After Rectal ...

A significant improvement was observed in the global health status between 1 and 6 months postoperatively (mean score 74.92 vs. 86.53; Δ = +11.62, p < 0.001).

Post-Operative Care of the Cancer Patient - PMC - NIH

Quality of recovery often relates to common adverse effects, such as pain, nausea, and vomiting, and long-term side effects of surgery. Patient- ...

Guidelines for postoperative care in gynecologic/oncology ...

Guidelines for postoperative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Item, Recommendation ...

Post-Surgery Monitoring for Cancer

Discover strategies for tracking recovery after cancer surgery using PROs and apps. Improve patient safety and outcomes with guided monitoring tools.