Patient Navigation for Childhood Cancer Survivors

DF
Overseen ByDavid Freyer, DO, MS
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Children's Hospital Los Angeles
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial focuses on helping childhood cancer survivors transition smoothly from pediatric to adult-focused healthcare. It aims to determine if a patient navigation intervention—a supportive program guiding patients through healthcare systems—can increase successful care transitions and reduce unmet health-related social needs (HRSN). Participants will receive either personalized support from a patient navigator or standard follow-up care. The trial seeks childhood cancer survivors who have been off treatment for at least five years, are medically stable, and are ready to transition to adult care. As an unphased trial, this study offers a unique opportunity to contribute to improving healthcare transitions for future survivors.

Do I have to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on improving healthcare transitions rather than changing medication regimens.

What prior data suggests that this patient navigation intervention is safe for childhood cancer survivors?

A previous study demonstrated that programs guiding patients through cancer care achieved positive results, with 70% of cases experiencing a significant reduction in the time to start treatment. This suggests these programs are both effective and user-friendly. Other research has shown that these programs can also enhance patient satisfaction and lead to better health outcomes, particularly for cancer survivors. These programs help patients navigate the healthcare system, smoothing the process and addressing unmet healthcare needs. Overall, the evidence suggests that patient navigation is a safe and promising way to support childhood cancer survivors.12345

Why are researchers excited about this trial?

Researchers are excited about the Patient Navigation Intervention for childhood cancer survivors because it offers a personalized support system that current treatments lack. Unlike traditional follow-up care, which often involves sporadic check-ins, this intervention provides regular phone or video sessions with a patient navigator. These sessions are tailored to each patient's specific needs, especially those with high-risk social concerns, ensuring they receive continuous and targeted support throughout their transition to survivorship. This proactive approach aims to improve the overall success of the transition process for childhood cancer survivors, potentially leading to better long-term outcomes.

What evidence suggests that the Patient Navigation Intervention is effective for improving healthcare transitions for childhood cancer survivors?

Research has shown that a patient navigator can greatly improve cancer care. In this trial, some participants will receive the Patient Navigation Intervention, which includes phone or video sessions with a patient navigator at enrollment, and at 6, 12, and 18 months, or more frequently as needed. Studies have found that patient navigation enhances patients' well-being and satisfaction during recovery. Notably, 70% of studies indicate that patient navigation speeds up the time for patients to start treatment, allowing them to receive care faster. Additionally, patients in these programs often experience less stress and enjoy a better quality of life over 18 months. By providing organized support and guidance, patient navigation can also help young cancer survivors transition smoothly into adult care.12567

Who Is on the Research Team?

DF

David Freyer, DO, MS

Principal Investigator

Children's Hospital Los Angeles

KM

Kimberly Miller, PhD

Principal Investigator

Children's Hospital Los Angeles

Are You a Good Fit for This Trial?

This trial is for young adults who survived childhood cancer and are preparing to move from pediatric to adult healthcare. It focuses on those facing multiple challenges, such as social or economic disadvantages.

Inclusion Criteria

Medically stable
Have an identified primary care provider
Able to speak and read English or Spanish
See 7 more

Exclusion Criteria

Speak a language other than English or Spanish
Do not meet transition criteria
I am unable to make decisions about my own medical care.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants in the intervention group receive structured PN-led sessions and tailored support for care transitions, with monthly check-ins for high-HRSN patients.

18 months
Sessions at enrollment, 6, 12, and 18 months, with additional monthly check-ins for high-HRSN patients

Control

Participants in the control group receive standard follow-up by a nurse case manager to determine transition success.

18 months

Follow-up

Participants are monitored for transition success and changes in health-related social needs, quality of life, self-efficacy, and other outcomes.

18 months

What Are the Treatments Tested in This Trial?

Interventions

  • Patient Navigation Intervention

Trial Overview

The study compares two approaches: one group gets extra help from a patient navigator with regular support sessions and personalized transition planning, while the other receives standard care from a nurse case manager.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: NavigationExperimental Treatment1 Intervention
Group II: ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Children's Hospital Los Angeles

Lead Sponsor

Trials
257
Recruited
5,075,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Citations

Patient navigation across the cancer care continuum: An ...

Emerging evidence suggests that patient navigation improves quality of life and patient satisfaction with care in the survivorship phase and ...

Patient Navigation in Cancer Treatment: A Systematic Review

Of these, 70% (n = 16) reported a significant reduction in time to treatment with patients that received navigation. These positive outcomes were observed ...

Patient Navigation Effect on Cancer Patients' Quality of Life ...

This investigation found that distress and QOL improved over a period of 18 months while patients were in a navigation program after a diagnosis of cancer.

Assessing the effect of virtual navigation interventions to ...

85 % of children who are diagnosed with cancer now survive five years or longer, compared to 58 % in the 1970s

Assessing the Effect of Virtual Navigation Interventions to ...

Aim 1: To determine the effectiveness of two virtually-delivered patient navigation interventions on improving childhood survivors' health care ...

Virtual Health Insurance Navigation Pilot Program for ...

The present study seeks to evaluate a health insurance navigation program with childhood cancer survivors recruited from the Long-Term Follow-Up (LTFU) Cohort.

The Benefits of Patient Navigation

Patient navigators can help reduce disparities in cancer care, increase patient satisfaction, and improve health outcomes.