Resistance Training for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether resistance training combined with either conditioning or cardio results in similar improvements in body composition, muscle mass, and blood pressure for women treated for breast cancer. Participants will join one of two groups: one performing resistance training with conditioning and the other with cardio. Women who have completed breast cancer treatment (excluding those still undergoing chemotherapy), have over three months of resistance training experience, and have been prescribed exercise as part of their care are ideal candidates for this study.
As an unphased trial, this study provides participants the chance to contribute to valuable research that could enhance exercise recommendations for breast cancer survivors.
What prior data suggests that this resistance training is safe for women treated with breast cancer?
Research has shown that resistance training is generally safe for breast cancer patients. It enhances muscle strength and quality of life without worsening lymphedema, a condition where fluid buildup causes swelling. Many participants experience improved mobility and reduced fatigue. For those combining resistance training with cardio, studies report gains in muscle strength and quality of life. Overall, evidence suggests these exercise routines are well-tolerated by patients, with few reports of negative effects.12345
Why are researchers excited about this trial?
Unlike traditional treatments for breast cancer that primarily focus on chemotherapy, radiation, or surgery, these new approaches incorporate physical fitness into the care plan. Resistance training combined with either cardio or conditioning offers a unique angle by enhancing physical strength, boosting cardiovascular health, and potentially improving recovery and quality of life for patients. Researchers are excited because these methods could offer non-invasive, holistic benefits that complement existing medical treatments, potentially helping patients manage the side effects of more traditional therapies and improve overall well-being.
What evidence suggests that this trial's treatments could be effective for breast cancer?
Research has shown that strength training benefits women treated for breast cancer. This trial will compare two exercise regimens: Resistance Training with Cardio and Resistance Training with Conditioning. Studies have found that combining strength exercises with cardio significantly boosts muscle strength, reduces fatigue, and improves overall quality of life. One study found that strength training can substantially lower the risk of death for breast cancer patients, making it a potentially life-saving activity. These exercises also promote a healthier balance of muscle and fat and reduce inflammation, which may lead to better health. Overall, exercise, including both cardio and strength training, has proven to enhance physical fitness and health for breast cancer survivors.12467
Who Is on the Research Team?
Colin Champ, MD, CSCS
Principal Investigator
AHN Radiation Oncology
Are You a Good Fit for This Trial?
This trial is for women who have been treated for breast cancer. Participants should be able to safely take part in exercise programs, as determined by the study team.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Exercise Program
Participants undergo either intense resistance training with conditioning or cardiovascular training
Follow-up
Participants are monitored for changes in muscle mass, fat mass, blood pressure, and other body composition metrics
What Are the Treatments Tested in This Trial?
Interventions
- Resistance Training with Cardio
- Resistance Training with Conditioning
Trial Overview
The study compares two types of exercise: resistance training combined with cardio versus resistance training combined with conditioning. It looks at effects on body composition, muscle mass, and blood pressure.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Lead Sponsor
Citations
Resistance Training in Breast Cancer Survivors - PMC - NIH
The trials reported significant improvement in muscle strength, fatigue, pain, quality of life, and minor changes in aerobic capacity.
Exercise Training Improves Strength and Quality of Life for ...
Supervised aerobic and resistance exercise can improve the physical performance and strength of patients living with metastatic breast cancer, ...
Protective effects of exercise on cardiotoxicity induced by ...
Conclusions. Exercise does not seem to be effective in avoiding the cardiotoxic effects of oncological treatment for breast cancer. Although exercise seems to ...
Study: Just One HIIT or Strength Workout Fights Cancer
Both workouts reduced the growth of cancer cells by about 25% in the lab. A single workout of either resistance training or HIIT also boosted ...
Effectiveness of exercise modalities on breast cancer patient ...
Overall exercise significantly improves the HRQOL, CRF and physical function in patients with BC. HRQOL was improved with all exercise types but ...
6.
oncologynewscentral.com
oncologynewscentral.com/article/survival-benefit-in-breast-cancer-patients-who-exerciseSurvival Benefit in Breast Cancer Patients Who Exercise
Resistance training significantly reduced the risk for death (hazard ratio [HR], 0.18; 95% confidence interval [CI], 0.04–0.83) compared with ...
Is Resistance Training Safe for Patients With Breast Cancer?
Structured resistance training is safe for breast cancer patients, improving arm muscle and reducing lymphedema during and after treatment.
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