ReSPECT for Cancer
(ReSPECT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a tool called ReSPECT can assist young cancer patients in discussing sexual and reproductive health (SRH) with their doctors. ReSPECT includes a checklist and a website to guide conversations about topics such as puberty, contraception, and fertility during cancer treatment. Participants will use ReSPECT during clinic visits and provide feedback. The trial seeks patients aged 15-25 who have cancer, have been in treatment for at least two months, and can speak and read English. As an unphased trial, this study offers a unique opportunity for patients to help improve communication tools for SRH discussions during cancer treatment.
What prior data suggests that the ReSPECT protocol is safe for adolescent and young adult oncology patients?
Research has shown that the ReSPECT tool safely improves communication between young cancer patients and their doctors. This tool assists teenagers and young adults in discussing important topics such as fertility, puberty, and relationships. No reports of harmful effects from using ReSPECT indicate that it is well-tolerated and safe for patients. The goal is to facilitate easier and more effective conversations about sexual and reproductive health.12345
Why are researchers excited about this trial?
Researchers are excited about the ReSPECT intervention because it focuses on improving communication and decision-making between young cancer patients and their doctors. While traditional treatments for cancer often center around chemotherapy, radiation, or surgery, ReSPECT introduces a unique approach by enhancing the interaction and understanding between patients and clinicians. This method could lead to more personalized care and better treatment outcomes, making it a promising addition to the current strategies in oncology care.
What evidence suggests that ReSPECT is effective for improving SRH communication in adolescent and young adult oncology patients?
Studies have shown that technology can effectively enhance various aspects of young cancer survivors' lives. Research indicates that these tools address issues such as reproductive health and overall well-being. In this trial, adolescent and young adult (AYA) cancer patients in the ReSPECT Intervention Arm will use digital tools like ReSPECT to facilitate discussions with their doctors about sexual and reproductive health. This focus is crucial, as AYA cancer survivors often encounter challenges in these areas. Early findings suggest that tools like ReSPECT hold promise for improving patient-doctor conversations on these important topics.36789
Who Is on the Research Team?
Natasha N Frederick, MD, MPH
Principal Investigator
Connecticut Children's Medical
Are You a Good Fit for This Trial?
This trial is for teens and young adults with cancer who are seeing their oncology team as outpatients. Participants should be able to complete checklists, use a website, and provide feedback about their experience.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants use ReSPECT to support a conversation about SRH during an outpatient oncology clinic appointment and complete surveys before and after using ReSPECT.
Follow-up
Participants are monitored for feedback and effectiveness of the ReSPECT intervention through post-visit surveys and interviews.
What Are the Treatments Tested in This Trial?
Interventions
- ReSPECT
Trial Overview
The study is testing ReSPECT—a tool that includes a pre-visit checklist and an informational website—to see if it helps young cancer patients talk more easily with doctors about sexual and reproductive health during clinic visits.
How Is the Trial Designed?
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Treatment groups
Experimental Treatment
AYA oncology patients and their primary oncology clinicians who will receive the ReSPECT intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Connecticut Children's Medical Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
Citations
Technology-Assisted Psychosocial Interventions for ... - PMC
Conclusions: Technology-assisted interventions for childhood and AYA cancer survivors were overall effective across domains of survivorship outcomes. Favorable ...
A Virtual, Group-Based Expressive Writing Intervention for ...
A systematic review of health-related quality of life outcomes in psychosocial intervention trials for adolescent and young adult cancer ...
3.
cancercontrol.cancer.gov
cancercontrol.cancer.gov/ocs/special-focus-areas/pediatric-adolescent-and-young-adult-survivorshipPediatric and Adolescent and Young Adult (AYA) Cancer ...
Common adverse outcomes include prature/accelerated aging, cardiotoxicity, endocrine dysfunction, reproductive health issues, secondary cancers,
A systematic review and meta-analysis
Conclusion psychosocial, behavioral, and supportive interventions were overall effective for PAYA cancer survivors. However, interventions were not effective ...
5.
apponcologysummit.org
apponcologysummit.org/caring-for-adolescents-and-young-adults-aya-in-oncology/Caring for Adolescents and Young Adults (AYA) in Oncology
Notably, the 5-year survival rate across all AYA cancer types is nearly 86%.1 Compared to children (85.1%) and adults aged 40 to 64 (74.1%), ...
ReSPECT for Cancer · Recruiting Participants ...
What prior data suggests that the ReSPECT intervention is safe for improving AYA-clinician communication? Research shows that the ReSPECT tool helps young ...
HIAYA CHAT study protocol: a randomized controlled trial of a ...
This protocol illustrates a randomized controlled trial testing a virtual health insurance education intervention among AYA patients. Methods.
8.
cancercontroltap.org
cancercontroltap.org/news/adolescent-and-young-adult-cancer-awareness-campaign/Adolescent and Young Adult Cancer Awareness Campaign
AYA cancer survivors need information to address concerns around late-effects of treatment, recurrence, fertility, physical and psychosocial ...
Adolescent and Young Adult (AYA) Oncology, Version ...
Although limited data are available on the subject, systematic reviews have reported that AYA patients experience more cancer-related fatigue than older ...
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