Online Wellness Program for Multiple Sclerosis

(DEW Trial)

ME
WS
Overseen ByWhitney Schley, Schley

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether an online wellness program can reduce fatigue and enhance mood and quality of life for people with progressive multiple sclerosis (MS). The program includes lessons on nutrition, stress management, and physical activity, along with coaching and support. Participants will be divided into two groups: one will start the program immediately, while the other will continue their usual care and access the program later. Ideal candidates for this trial have progressive MS, experience significant fatigue, and can prepare meals at home. As an unphased trial, this study offers a unique opportunity to contribute to understanding how lifestyle changes can impact MS symptoms.

What prior data suggests that this online wellness program is safe for people with multiple sclerosis?

Research has shown that online wellness programs and virtual exercise platforms can be safe and beneficial for people with multiple sclerosis (MS). Studies have found that participating in online health education programs can enhance knowledge and improve quality of life for those with MS, without causing major side effects.

For instance, a study on a similar online course found that it increased resilience and confidence in managing the condition. Additionally, digital health platforms that include exercise are generally well-received, with participants reporting improved physical health.

Overall, online wellness programs, like the one in this study, are usually well-tolerated and pose no significant risks. They provide a safe and convenient way to support health and wellness for people with MS.12345

Why are researchers excited about this trial?

Researchers are excited about the online wellness program for multiple sclerosis because it offers a unique approach to managing the condition. Unlike traditional treatments that often focus on medication, this program leverages digital platforms to promote overall well-being and physical activity, which are crucial for managing symptoms. The convenience of accessing these resources online allows for greater flexibility and accessibility, potentially enhancing patient adherence and engagement. This innovative method could complement existing therapies by empowering patients to actively participate in their care, which is a promising shift in managing multiple sclerosis.

What evidence suggests that this online wellness program is effective for multiple sclerosis?

Studies have shown that exercise is safe and beneficial for people with multiple sclerosis (MS). Research indicates that various exercise programs can reduce MS symptoms, enhance physical abilities, and increase energy levels. One study found that exercise using virtual reality significantly improved movement in people with MS. Another study showed that a 12-week strength training program increased strength in women with MS without causing more relapses or side effects. This trial will evaluate an online wellness program focused on exercise, which could help reduce fatigue and improve the quality of life for people with MS. Participants in the intervention arm will engage with an online wellness program and virtual exercise platform, while those in the waitlist control will continue with usual care as directed by their neurologist.678910

Are You a Good Fit for This Trial?

This trial is for people aged 45 to 70 with progressive multiple sclerosis who are experiencing significant fatigue. Participants must be able to use online platforms and complete study activities.

Inclusion Criteria

Ability to prepare, or availability of someone in the household to prepare, home-cooked meals
Willingness to commit to the study diet, 4-7-8 breathing technique, and a structured exercise program
Access to high-speed internet with ownership of a device capable of audio/video streaming and accessing online programming
See 5 more

Exclusion Criteria

Measurement of Body Mass Index (BMI) less than 19
Clinical diagnosis of psychiatric disease making study adherence difficult (e.g., schizophrenia) or an active eating disorder (anorexia, bulimia, binge eating, orthorexia)
Documentation of moderate or severe mental impairment (greater than or equal to 5 errors) as measured by the validated Short Portable Mental Health Questionnaire (SPMHQ)
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week
Online assessment

Run-in Period

Participants complete a 7-day run-in period to confirm interest and ability to complete study activities

1 week
Online participation

Treatment

Participants in the intervention group receive access to the online wellness program and complete five self-paced education modules over 6 months

6 months
Monthly group coaching calls via Zoom

Follow-up

Participants complete final surveys about their symptoms, quality of life, and experience with the program

1 week
Online surveys

What Are the Treatments Tested in This Trial?

Interventions

  • Online wellness course and online exercise platform

Trial Overview

The study compares an online wellness program—including self-paced courses, group coaching, and exercise resources—to usual care. Participants are randomly assigned to either start the program right away or after a 6-month wait period.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Intervention armExperimental Treatment1 Intervention
Group II: Waitlist controlPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Iowa

Lead Sponsor

Trials
486
Recruited
934,000+

Citations

Delivering healthcare provider training for remote exercise ...

In this project, Associate Professor Learmonth will develop and test an online education tool to train MS exercise physiologists, occupational therapists and ...

Wheelchair Exercise Training for Multiple Sclerosis

Research has shown that exercise is safe and beneficial for people with multiple sclerosis (MS). Studies have found that various exercise programs can reduce MS ...

Feasibility of Remote Exercise Training... | Clinical Trial

The FERLA MS study is a randomized controlled trial aimed at investigating the feasibility and effectiveness of a remotely-delivered exercise ...

New research shows virtual reality exercises for arm and hand ...

Exercise has been shown to have tremendous benefits for individuals with MS, including improved physical function, increased energy levels, ...

Exercise Training Program for Multiple Sclerosis · Info ...

Research shows that exercise is safe for people with multiple sclerosis (MS). Studies have found no increased risk of relapses or serious side effects compared ...

Study Details | NCT04564495 | Home Based Tele-exercise ...

This study aims to examine how effective seated Zoom exercise classes are for a person with CNI for addressing cardiovascular health, physical wellness and ...

Evaluating the impact of the Understanding Multiple ...

We report on the impact of participating in an online health education program on multiple sclerosis (MS) related knowledge and other health outcomes.

Do internet resources align with exercise training and ...

Conclusion: Many online recourses regarding physical activity and exercise training for MS were either inconsistent with the established PAGs or did not address ...

Physical activity assessment in patient care and ...

ExerciseRx digital health platform incorporating smartphone and wearable step count tracking, personalized activity goals, and AI/ML home ...

A custom-built step exergame training programme to prevent ...

The step exergame training programme did not reduce falls among people with MS. However, it significantly improved choice-stepping reaction time