Spinal Cord Stimulation for Multiple Sclerosis
(eSTIM-MS Home Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a pilot study designed to test the feasibility of in-home, non-invasive (transcutaneous, applied by surface electrodes over the skin) electrical spinal cord stimulation combined with exercises for restoring upper extremity sensorimotor function in adults with multiple sclerosis.
Participants with multiple sclerosis and impaired upper extremity function will complete 8-weeks of hand/arm exercises combined with spinal cord stimulation performed at home with the help of a partner.
The investigators hypothesize that:
1. in-home transcutaneous spinal cord stimulation combined with hand/arm exercises will be feasible and acceptable by participants
2. in-home transcutaneous spinal cord stimulation combined with hand/arm exercises will lead to improvements in upper extremity function after 8-weeks
3. in-home transcutaneous spinal cord stimulation combined with therapy will lead to improvements in symptoms related to quality of life (pain, spasticity, and bladder symptoms)
Who Is on the Research Team?
Sarah Simmons, MD, PhD
Principal Investigator
University of Washington
Are You a Good Fit for This Trial?
This trial is for adults with multiple sclerosis who have trouble using their hands or arms. Participants need to be able to do exercises at home, likely with help from a partner.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Spinal Cord Stimulation + Hand/arm Exercises
Trial Overview
The study tests if doing hand and arm exercises together with non-invasive electrical stimulation of the spinal cord (using electrodes on the skin) at home can improve hand and arm function in people with MS over 8 weeks.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
The 8-week intervention will consist of approximately 1-hour sessions, 3-4x times per week. These sessions will occur in the participant's home, during which hand/arm exercises and transcutaneous spinal cord stimulation (tSCS) will be performed. A caregiver or partner will assist with electrode placement and tSCS administration. Exercises are similar to what would be prescribed by an occupational therapist for an outpatient home exercise program, and include: repetitive activities of gross upper limb movement, isolated finger movements, bimanual task performance, simple and complex pinch, and grip performance.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Washington
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.