60 Participants Needed

Resistance Training for Parkinson's Disease

CP
JF
Overseen ByJoseph F. Signorile, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Miami
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how different types of resistance training can help people with Parkinson's disease improve muscle strength and daily activity performance. Participants will engage in either a high-speed power resistance training program or a periodized resistance training program, which mixes different exercise phases. It targets individuals with Parkinson's in the early to moderate stages who can walk unassisted. The goal is to determine which training method more effectively boosts strength and daily function. As an unphased trial, this study provides participants the opportunity to contribute to valuable research that could enhance treatment options for Parkinson's disease.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that exercise, including resistance training, is generally safe for people with Parkinson's disease. Studies on structured resistance training indicate it can improve balance, strength, and daily function without major safety concerns. Similarly, power resistance training is considered safe and helpful for improving movement symptoms. Both types of resistance training are well-tolerated, with no major negative effects commonly reported. This suggests these exercises are safe options for managing symptoms in Parkinson's patients.12345

Why are researchers excited about this trial?

Researchers are excited about resistance training for Parkinson's disease because it offers a unique approach compared to standard treatments like medication and physical therapy. Periodized resistance training involves structured and progressive strength exercises, which may help improve muscle strength and motor function over an extended period. Power resistance training, on the other hand, focuses on high-speed exercises, potentially enhancing muscle power and agility more quickly. These methods could complement existing treatments by directly targeting muscle performance, offering a new dimension to managing Parkinson's symptoms.

What evidence suggests that this trial's treatments could be effective for Parkinson's disease?

Research has shown that structured resistance training can help people with Parkinson's disease improve movement, balance, and muscle strength. Studies have found that this exercise type supports better movement and eases daily tasks. In this trial, participants will be assigned to either Periodized Resistance Training or Power Resistance Training. Periodized Resistance Training has proven helpful in managing Parkinson's symptoms. Similarly, Power Resistance Training effectively increases muscle strength and improves the quality of life for those with mild to moderate Parkinson's. Some evidence suggests that power training can enhance physical performance, though it may not always surpass other methods. This trial evaluates both training types for their potential benefits.23678

Who Is on the Research Team?

JF

Joseph F. Signorile, PhD

Principal Investigator

University of Miami

Are You a Good Fit for This Trial?

This trial is for older adults who can communicate in English, have Parkinson's Disease at stages 1-3, and can walk unassisted for 50 meters. It excludes those with cardiovascular or neuromuscular diseases that affect training ability, recent limb injuries/surgeries preventing weight training, or inflammatory/autoimmune conditions.

Inclusion Criteria

Able to understand and communicate in English
My Parkinson's is in the early to mid stages.
I can walk 50 meters without help.

Exclusion Criteria

I have an injury or recent surgery on my arms or legs that stops me from lifting weights.
I do not have heart or muscle conditions that stop me from joining a training program.
I do not have conditions like rheumatoid arthritis or other serious illnesses.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either periodized resistance training or high-speed power resistance training

12 weeks
24 sessions (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Periodized Resistance Training
  • Power Resistance Training
Trial Overview The study compares high-speed power resistance training with periodized resistance training (cycles of hypertrophy, strength and power) to see which is better for muscle strength/power and daily performance in older adults with Parkinson's disease.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Periodized Resistance TrainingExperimental Treatment1 Intervention
Group II: Power Resistance TrainingActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Miami

Lead Sponsor

Trials
976
Recruited
423,000+

Citations

Effectiveness of aerobic and resistance training on the motor ...Aerobic and resistance training are common complementary therapies to improve motor symptoms in people with Parkinson's disease (PD).
Feasibility and preliminary efficacy of an online home- ...Periodized resistance training with and without functional training improves functional capacity, balance, and strength in Parkinson's disease.
Power vs strength training to improve muscular ...The primary purpose of this study was to compare the effects of ST and PT on measures of strength, power, balance and functional movement in persons with PD.
4.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/33927114/
Periodized Resistance Training With and Without ...We conclude that both exercise strategies can be equally effective at improving functional capacity, balance, and muscular strength in individuals with PD.
(PDF) Periodized Resistance Training With and Without ...Periodized resistance training with and without functional training improves functional capacity, balance, and strength in Parkinson's disease.
Physical exercise for people with Parkinson's diseasePhysical exercise is effective in managing Parkinson's disease (PD), but the relative benefit of different exercise types remains unclear.
FIGHT-PD: A feasibility study of periodized boxing training ...Nine of 10 participants showed improvement in UPDRS motor score. Conclusions: FIGHT-PD provides a depth of feasibility and safety data,.
Resistance Training for Parkinson's DiseaseThis study will compare the effects of high-speed power resistance training to periodized training, which includes cycle of hypertrophy, ...
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