Vagal Auricular Stimulation for Motion Sickness

(VAMOS Trial)

LM
Overseen ByLuca McKerley Coronado, BA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Spaulding Rehabilitation Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study aims to understand the mechanisms underlying nausea response in the brain stem, and the effect of vagal nerve stimulation on nausea.

Are You a Good Fit for This Trial?

This trial is for adults who experience motion sickness or chronic nausea. People with certain medical conditions, implanted electronic devices, or other factors that could interfere with nerve stimulation may not be able to participate.

Inclusion Criteria

Ability to give written consent and participate in behavioral intervention in English
Avoidance of alcohol, nicotine, and caffeine for 24 hours prior to study session
Motion Sickness Susceptibility Questionnaire (MSSQ) percentile score greater than 60
See 2 more

Exclusion Criteria

I have ongoing nausea caused by my medications or stomach issues.
I have had seizures in the past or currently have seizures.
I have severe problems with my body's automatic functions, like heart rate or blood pressure.
See 14 more

What Are the Treatments Tested in This Trial?

Interventions

  • UROStim

Trial Overview

The study is testing a device called UROStim, which uses gentle electrical stimulation on the ear to activate the vagus nerve and see if it can reduce feelings of nausea caused by motion sickness.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Visit 1: Sham stimulation; Visit 2: Active StimulationExperimental Treatment1 Intervention
Group II: Visit 1: Active stimulation; Visit 2: Sham stimulationExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Spaulding Rehabilitation Hospital

Lead Sponsor

Trials
143
Recruited
11,200+

National Center for Complementary and Integrative Health (NCCIH)

Collaborator

Trials
886
Recruited
677,000+