Hormone Replacement Therapy for Menopause
What You Need to Know Before You Apply
What is the purpose of this trial?
This study investigates the influence of sex hormones and exercise on age-related neuromuscular decline in females. Specifically, the research aims to evaluate how hormonal variations impact both age-associated neuromuscular decline and the subsequent adaptations to exercise and resistance training.
Age-related declines in neuromuscular function are especially pronounced in females, potentially due to the sharp drop in estradiol after menopause. This project will compare postmenopausal females who have not taken hormonal therapy (HT) to age-matched females taking HT.
Are You a Good Fit for This Trial?
This trial is for postmenopausal women, both those who are currently taking hormone therapy and those who have never taken it. Participants should be generally healthy and able to take part in a strength training program.Exclusion Criteria
What Are the Treatments Tested in This Trial?
Trial Overview
The study compares how high-resistance strength training affects muscle and nerve function in two groups of postmenopausal women: those using hormone replacement therapy (HRT) and those not using HRT.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Postmenopausal females who are currently taking hormone replacement therapy
Postmenopausal females who have no history of taking hormone replacement therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan
Lead Sponsor
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