Photobiomodulation for Postoperative Pain

SB
Overseen BySophie Bengson
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Minnesota
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This randomized, double-blind controlled clinical trial will evaluate whether adjunctive photobiomodulation improves recovery after nonsurgical root canal treatment in adults with teeth diagnosed with symptomatic apical periodontitis.

Participants will receive standard nonsurgical root canal treatment and will be randomized to adjunctive photobiomodulation using the Fotona LightWalker Nd:YAG laser or to an identical simulated laser procedure without laser energy delivery.

The study will evaluate mechanical allodynia using maximum occlusal force measurements comparing the treated tooth with the contralateral asymptomatic tooth. Postoperative pain will also be assessed using the Numeric Rating Scale after percussion testing.

Who Is on the Research Team?

RO

Ronald Ordinola-Zapata

Principal Investigator

University of Minnesota

Are You a Good Fit for This Trial?

This trial is for adults who need a nonsurgical root canal due to painful tooth conditions like abscess or inflamed dental pulp. People with these symptoms and no major health issues can join.

Inclusion Criteria

I have a tooth with painful inflammation at the tip of its root.
Able and willing to return for the scheduled follow-up visit 7 to 10 days after treatment
I am 18 years old or older.
See 6 more

Exclusion Criteria

I cannot or do not want to come back for follow-up visits.
Any medical, physical, or cognitive condition that would prevent safe participation or completion of study procedures
I have a tooth that cannot be saved due to severe damage or fracture.
See 21 more

What Are the Treatments Tested in This Trial?

Interventions

  • Photobiomodulation

Trial Overview

The study compares standard root canal treatment plus real laser therapy (photobiomodulation) versus standard care with a fake laser procedure. Participants are randomly assigned, and neither they nor the researchers know which group they're in.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Adjunctive PhotobiomodulationExperimental Treatment1 Intervention
Group II: Sham PhotobiomodulationPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Minnesota

Lead Sponsor

Trials
1,459
Recruited
1,623,000+