Arthrocentesis for ACL Tears
(ASPIRATE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The ASPIRATE trial is a randomized controlled trial evaluating the effects of pre- and post-operative knee joint aspiration in patients with an ACL injury. The study aims to determine if removing knee joint fluid can mitigate the increasing inflammation after surgery, reduce quadriceps atrophy, improve short-term pain, enhance functional recovery, and lower long-term rates of post-traumatic knee osteoarthritis.
Who Is on the Research Team?
Jelle van der List, MD, PhD
Principal Investigator
Ohio State University
Are You a Good Fit for This Trial?
This trial is for people who have recently injured or torn their ACL (a major knee ligament) and are planning to have surgery. Participants should not have other serious injuries, infections, or health conditions that could affect the study.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Knee Aspiration
Trial Overview
The study compares two groups: one group has fluid removed from their knee joint before and after ACL surgery (knee aspiration), while the other group does not. The goal is to see if this helps with pain, swelling, muscle strength, and recovery.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Each subject that is randomized to this arm will receive a knee aspiration both before and after ACL surgery.
Each subject that is randomized to this arm will not receive an intervention and will only complete questionnaires.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University
Lead Sponsor
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