Epidural Analgesia Techniques for Labor Pain
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores two methods of managing labor pain using epidural analgesia. It compares a continuous flow of pain relief medication (Continuous Infusion) with a method that administers doses at intervals (Programmed Intermittent Epidural Bolus). Researchers aim to determine if the interval method uses less medication overall. Pregnant women in early labor, planning to use epidural pain relief and without certain medical conditions like gestational diabetes or multiple pregnancies, may be suitable for this study. As an unphased trial, it offers participants the chance to contribute to important research that could enhance pain management options for future mothers.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you have any pregnancy-related conditions or a history of chronic pain, you may not be eligible to participate.
What prior data suggests that these epidural analgesia techniques are safe for labor pain management?
Research has shown that a programmed intermittent epidural bolus (PIEB) for labor pain offers certain safety benefits. Studies have found that PIEB is associated with fewer unexpected doctor visits and a lower incidence of muscle weakness compared to continuous epidural infusion (CEI). Specifically, muscle weakness occurred in about 22% of cases with PIEB, compared to about 28% with CEI.
Patients using PIEB also reported higher satisfaction during labor. There were no significant differences in cesarean delivery rates, indicating that PIEB did not lead to more serious interventions.
Overall, PIEB appears well-tolerated and offers advantages over traditional methods like CEI, suggesting it is a safe option for managing labor pain.12345Why are researchers excited about this trial?
Researchers are excited about exploring new epidural analgesia techniques for labor pain because these methods could offer more effective pain management. Unlike the traditional continuous infusion, which provides a steady flow of medication, the programmed intermittent epidural bolus technique delivers medication at set intervals. This approach might enhance pain relief and reduce the total amount of medication needed, potentially leading to fewer side effects for both the mother and baby. Additionally, combining it with patient-controlled analgesia gives mothers more control over their pain management during labor.
What evidence suggests that this trial's treatments could be effective for labor pain?
This trial will compare two epidural analgesia techniques for labor pain: the continuous infusion method and the programmed intermittent epidural bolus (PIEB) method. Studies have shown that PIEB effectively manages labor pain. Research indicates that PIEB often leads to lower pain levels and reduces the need for additional pain relief. It also tends to increase maternal satisfaction. Compared to continuous infusion, PIEB may use less medication and result in fewer assisted deliveries, although results can vary. Overall, PIEB appears promising for providing effective pain relief during labor.56789
Who Is on the Research Team?
Geneviève Rivard, Dr.
Principal Investigator
Université de Sherbrooke
Are You a Good Fit for This Trial?
This trial is for pregnant women in labor, whether it's their first child or not. They must be at least 18 years old and have agreed to epidural pain relief. Their overall health should be good to moderately impaired (ASA I-III), and they need to be in early labor with a cervical dilation of 6cm or less.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either a programmed intermittent epidural bolus or continuous infusion combined with patient-controlled epidural analgesia during labor
Follow-up
Participants are monitored for outcomes such as cesarean section, patient satisfaction, and pain evaluation
What Are the Treatments Tested in This Trial?
Interventions
- Continuous Infusion
- Programmed Intermittent Epidural Bolus
Continuous Infusion is already approved in European Union, United States, Canada for the following indications:
- Labour analgesia
- Labour analgesia
- Labour analgesia
Find a Clinic Near You
Who Is Running the Clinical Trial?
Université de Sherbrooke
Lead Sponsor