FANS vs CVAC for Kidney Stones

This trial compares two new devices, FANS and CVAC, used in procedures to remove kidney stones. Both devices are ureteroscopes, which help doctors see and remove stones from the urinary tract, but they employ different suction technologies. The trial aims to determine which device more effectively achieves a stone-free status for patients. Individuals with kidney stones measuring 8-20 mm and diagnosed with nephrolithiasis may be suitable candidates for this trial. As an unphased trial, it provides patients the chance to contribute to innovative research that could enhance future kidney stone treatments.

The trial information does not specify whether you need to stop taking your current medications.

Previous studies have shown that both the FANS and CVAC systems are safe for treating kidney stones.

Research indicates that FANS is well-tolerated, showing similar safety results regardless of whether the stones are infected. Patients using FANS experienced less bleeding and had shorter hospital stays compared to some other treatments.

Studies have also shown that the CVAC system is safe and effective. It successfully clears stones and leaves few leftover fragments. Real-world studies confirm its safety in various settings.

Researchers are excited about the FANS and CVAC techniques for kidney stones because these methods offer potentially more efficient and less invasive options compared to traditional approaches like shock wave lithotripsy or standard ureteroscopy. The Flexible and Navigable Suction Ureteroscopy (FANS) allows for precise navigation and suction of stone fragments, potentially reducing the risk of residual stones and complications. Meanwhile, the CVAC suction ureteroscopy arm focuses on effectively removing stone fragments through enhanced suction capabilities, which could mean quicker recovery times and improved patient comfort. Both techniques aim to improve the overall success rate of kidney stone removal and provide a smoother experience for patients.

This trial will compare the effectiveness of CVAC and FANS for kidney stone removal. Research has shown that both CVAC and FANS effectively remove kidney stones. Participants in the CVAC arm may experience quick stone clearance; one study found it took about 47 seconds, leaving very little behind. Meanwhile, participants in the FANS arm may benefit from a 99% success rate in achieving a stone-free state, while maintaining low pressure inside the kidney to prevent damage during removal. Both devices are considered safe and effective for treating kidney stones.¹⁴⁵⁶⁷