Ketone Monoester + Dietary Protein for Recovery
((KET-YOUNG-M) Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in young trained males. This trial will compare the difference in phenylalanine metabolism between the ketone monoester and control conditions. Secondary outcomes including plasma amino acid, plasma insulin, plasma glucose, capillary blood beta-hydroxybutyrate concentrations and whole body myofibrillar protein breakdown rate (k) will be explored as secondary measures. Ketone monoester supplementation with protein in the post-resistance exercise period will be compared to the control condition of just protein in the post-resistance exercise period.
Who Is on the Research Team?
Tyler A Churchward-Venne, Ph.D
Principal Investigator
McGill University
Are You a Good Fit for This Trial?
This trial is for young men who regularly do resistance training. Participants should be healthy and able to exercise, with no major health conditions that would prevent safe participation.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Dietary Protein (PRO)
- Ketone Monoester + Dietary Protein (KET+PRO)
Trial Overview
The study compares the effects of taking ketone monoester plus protein versus just protein after weightlifting on how the body processes proteins. It looks at changes in muscle breakdown and amino acid levels.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
0.36 g/kg body weight of Ketone monoester (R)-3-hydroxybutyl (R)-3-hydroxybutyrate and 0.3 g of protein/kg body weight from whey protein hydrolysate dissolved in 250 mL of sugar-free Powerade with the addition of stevia and bitters to improve and homogenize taste between treatments.
0.3 g of protein/kg body weight from whey protein hydrolysate dissolved in 250 mL of sugar-free Powerade with the addition of stevia and bitters to homogenize taste between treatments.
Find a Clinic Near You
Who Is Running the Clinical Trial?
McGill University
Lead Sponsor
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