Family-Partnered Care for ICU Delirium
(ACTIVATE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs. Family members of critically ill patients are also at risk for adverse consequences such as depression and anxiety.
One strategy that may help to improve outcomes is to engage family members in the prevention, detection, and management of delirium. This study will employ an educational module to educate families on delirium symptoms, how delirium can be identified, and how to prevent and manage delirium using non-pharmacological strategies.
Family member delirium detection may result in earlier and more accurate recognition of delirium as well as meaningful family involvement, and ultimately the potential for better patient and family outcomes. This study aims to determine the efficacy of employing family-administered delirium prevention, detection, and management in the critically ill, compared to standard of care. We hypothesize that family-administered delirium prevention, detection, and management in the critically ill will be superior to standard of care in:
1. Reducing psychological distress in family members,
2. Reducing the prevalence, duration, and severity of delirium in critically ill patients,
3. Increasing delirium identification in medical charts,
4. Increasing delirium knowledge in family members of critically ill patients, and
5. Reducing the burden of delirium experienced by family members and caregivers
Who Is on the Research Team?
Kirsten Fiest, Ph.D.
Principal Investigator
University of Calgary
Are You a Good Fit for This Trial?
This trial is for critically ill patients in the ICU and their family members. Patients must be at risk for or experiencing delirium. Family members should be willing to participate in education and care activities related to delirium prevention, detection, and management.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Delirium Education, Prevention, and Management
Trial Overview
The study compares standard ICU care with an added program where families receive training on how to spot, prevent, and help manage delirium using non-drug methods. The goal is to see if involving families improves outcomes for both patients and their loved ones.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Patients and family caregivers will receive standard of care, which varies by study site, but includes guideline-recommended interventions by the clinical team to prevent and manage delirium. Additionally, they will receive a family-partnered delirium care intervention comprised of two components: 1) Education and 2) Family administered delirium prevention, detection, and management activities.
Patients and family caregivers will receive standard of care, which varies by study site, but includes guideline-recommended interventions by the clinical team to prevent and manage delirium.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Calgary
Lead Sponsor
Canadian Institutes of Health Research (CIHR)
Collaborator
University of Alberta
Collaborator
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