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Essential Oil Blend for Immune Support

(OGS Trial)

NS
Overseen ByNicole Stevens, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: dōTERRA International

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines the safety and effectiveness of an essential oil blend for boosting the immune system. Researchers divide participants into groups to test the oils in various ways: diffusing them in the air, applying them on the skin, taking them in capsules, or using a combination of these methods, while some will use a placebo. They will measure changes in immune health indicators and overall well-being. This trial suits individuals aged 18-45 who are healthy, can commit to using the product for 30 days, and do not frequently use essential oils. As an unphased trial, it offers a unique opportunity to explore the potential benefits of essential oils on immune health.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

A previous study showed that essential oils can be safely used when diffused in well-ventilated spaces. Diffusing oils for about 30 minutes at a time is important to avoid risks, especially for those with breathing issues. For skin application, essential oils should be mixed with another substance to prevent irritation, and they are generally safe when used this way.

However, swallowing essential oils can be risky. Research has shown that consuming them might irritate the mouth or stomach. They should not be taken undiluted or without expert advice, as this can lead to problems like toxicity.

Proper use is key to safety when using essential oils in any form. Always follow instructions and guidelines to minimize risks.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about the Essential Oil Blend for Immune Support because it offers a unique approach compared to traditional treatments for boosting immunity, such as vaccines or synthetic supplements. Unlike standard methods, this treatment utilizes natural essential oils, which may provide immune support through aromatic diffusion, topical application, and oral ingestion. Each method of delivery—whether inhaled, applied to the skin, or taken as a capsule—allows the body to absorb the oils differently, potentially offering a broad spectrum of benefits. This natural and versatile approach is what sets it apart and makes it a promising area of exploration for enhancing immune health.

What evidence suggests that this trial's treatments could be effective for immune support?

Research has shown that essential oils might support the immune system in various ways. In this trial, participants will be assigned to different arms to test the investigational essential oil blend. Diffusing oils like eucalyptus and tea tree may strengthen immune defenses during cold and flu seasons. Participants in the "Aromatic - Active" arm will diffuse the essential oil blend overnight. Applying essential oils like eucalyptus and ginger on the skin might boost immune function by interacting with immune cells. Participants in the "Topical - Active" arm will apply the essential oil blend topically. Ingesting oils like thyme and eucalyptus could provide antibacterial and anti-inflammatory benefits, supporting immune health. Participants in the "Internal - Active" arm will ingest capsules containing the essential oil blend. Some studies suggest that using essential oils in multiple ways can enhance their effectiveness in promoting immune function. This will be tested in the "Combined - Active" arm, where participants will use all three methods.678910

Who Is on the Research Team?

NS

Nicole Stevens, PhD

Principal Investigator

DoTERRA International LLC.

Are You a Good Fit for This Trial?

This trial is for healthy men and women aged 18-45 who can attend study visits, follow instructions, and avoid using essential oils outside the study. People with allergies to essential oils, certain health conditions (like asthma or heart disease), tobacco users, pregnant or breastfeeding women, and those recently using essential oils without a washout period cannot join.

Inclusion Criteria

Willing to refrain from use of essential oils (topical, aromatic, or internal) outside of the study during the study period
I am a healthy adult between 18 and 45 years old.
Able to read, write, and understand English
See 3 more

Exclusion Criteria

Use of recreational drugs
Known allergy or hypersensitivity to essential oils or components of placebo preparation
Current use of tobacco products including smoking, vaping, or chewing tobacco
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the investigational essential oil-based product system or placebo for 30 days through aromatic, topical, internal, or combined use

4 weeks
2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Essential Oil Blend

Trial Overview

The study tests an essential oil blend used in different ways—aromatic (diffused overnight), topical (applied to skin before bed), internal (oral capsules twice daily), or combinations—compared to a placebo. Participants are randomly assigned treatments for 30 days in a double-blind design.

How Is the Trial Designed?

8

Treatment groups

Experimental Treatment

Placebo Group

Group I: Topical - ActiveExperimental Treatment1 Intervention
Group II: Internal - ActiveExperimental Treatment1 Intervention
Group III: Combined - ActiveExperimental Treatment1 Intervention
Group IV: Aromatic - ActiveExperimental Treatment1 Intervention
Group V: Aromatic - PlaceboPlacebo Group1 Intervention
Group VI: Topical - PlaceboPlacebo Group1 Intervention
Group VII: Internal - PlaceboPlacebo Group1 Intervention
Group VIII: Combined - PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

dōTERRA International

Lead Sponsor

Trials
7
Recruited
580+

Citations

Boosting Your Immune System with Essential Oil Recipes.

For a basic blend, use 3 drops of lavender and 2 drops of eucalyptus oil. This mix can help you breathe easier and feel more relaxed.

Diffuser Blends To Support Your Immune System

Powerful diffuser blend recipes to support your immune system during cold and flu season. Featuring eucalyptus, tea tree, frankincense, and more.

(PDF) The Smart Way for Diffusing Essential Oils!

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6 Amazing Benefits of Diffusing Essential Oils

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When mixed together, these oils create a synergistic effect, which research has shown can literally kill the flu virus!

A Review on Essential Oils Supporting the Immune System

Effects of a blend of thyme, peppermint and eucalyptus essential oils on growth performance, serum lipid and hepatic enzyme indices, immune ...

Aromatherapy: Do Essential Oils Really Work?

An integrative medicine expert weighs in on what essential oils are good for, what the research has found and how you can safely use them.

Essential Oil Safety: Avoiding Top 3 Mistakes in Usage

When diffusing essential oils: Use oils in a well-ventilated space Diffuse for 30-minute intervals, followed by breaks Ensure pets—especially ...

How to Use Essential Oils Safely

Essential oils are not explosive, and they are safe when used in a diffuser, but there is some degree of risk. Burners that are lit with a candle flame

Essential Oils: More Harmful Than Helpful?

Essential oils should be used with caution by individuals with respiratory conditions.