60 Participants NeededMy employer runs this trial

Environmental Pollutant Detox for Infertility

AM
Overseen ByAbigail Mancuso, MD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Abigail Mancuso
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Environmental pollutants are present in many aspects of everyday life. Exposures to common household products, such as food packaging and cookware, may affect reproductive health. Many of these environmental toxicants are known as "endocrine disrupting chemicals" because they can interfere with the body's hormone systems. Our study aims to create a guide that explains common sources of environmental toxicants and offer practical steps to reduce exposure. The investigators will evaluate how well participants understand this information and how consistently the intervention is maintained over time.

To assess whether these changes reduce environmental pollutant exposure, the investigators will measure levels of two classes of toxicants within the urine and blood at the beginning, middle and end of the study in patients struggling with infertility that are planning in vitro fertilization (IVF) treatment. The investigators will also measure the same chemicals in follicular fluid (fluid which surrounds developing eggs in the ovary) and seminal fluid (fluid which surrounds the sperm in semen) and compare these levels to samples from similar patients who did not receive the education or make environmental changes. The goal of this project is to determine whether simple changes to reduce exposure to environmental pollutants can lower chemical levels of toxicants in the body and whether this may ultimately impact outcomes for patients undergoing in vitro fertilization.

Are You a Good Fit for This Trial?

This trial is for people with unexplained infertility (no clear male or female cause found) who are planning to undergo IVF treatment.

Inclusion Criteria

I have been diagnosed with unexplained infertility.

What Are the Treatments Tested in This Trial?

Interventions

  • Environmental Pollutant Detox

Trial Overview

The study tests whether following a guide to reduce exposure to everyday environmental pollutants can lower levels of certain chemicals in the body. Participants' urine, blood, and reproductive fluids will be checked before, during, and after making these changes.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Plastic DetoxExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Abigail Mancuso

Lead Sponsor

American Society for Reproductive Medicine

Collaborator

Trials
1
Recruited
190+

American Society for Reproductive Medicine

Collaborator