Cooling Devices for Hyperthermia
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to identify a blood test that detects signs of heat strain in the body and to evaluate devices that aid in cooling. Participants will engage in treadmill exercises in a lab setting and will use either a cooling bandana during exercise or a hand cooling table after exercise. Individuals who regularly exercise and are in good general health, without heart, kidney, or lung diseases, may be suitable candidates for this trial. As an unphased trial, this study provides participants the chance to contribute to innovative research that could lead to new methods for managing heat strain.
Do I have to stop taking my current medications for the trial?
Yes, you will need to stop taking medications that affect temperature or inflammation, like steroids or NSAIDs, to participate in the trial.
What prior data suggests that these cooling devices are safe for use in humans?
Studies have shown that cooling bandanas are safe and do not cause negative side effects. They cool the body through evaporation, making them easy to use in hot weather or during physical activity. Made from safe materials, these bandanas are convenient and effective.
Hand cooling tables are also safe for use after exercise. They lower body temperature by cooling the hands and forearms, effectively reducing body heat without harm.
Both cooling bandanas and hand cooling tables have been used in various situations without reports of serious side effects. They are designed to manage body heat safely during and after exercise.12345Why are researchers excited about this trial?
Researchers are excited about these cooling techniques because they offer a non-invasive way to manage hyperthermia, which is a common challenge for athletes and individuals exposed to high temperatures. Unlike traditional methods such as medications or rest, these techniques use physical cooling devices like a bandana and a hand cooling table to help regulate body temperature. The cooling bandana provides direct cooling during exercise, while the hand cooling table aids in recovery. This trial could reveal how effective these devices are in quickly and safely bringing down body temperature, potentially offering a practical solution for managing heat-related stress.
What evidence suggests that these cooling devices are effective for hyperthermia?
This trial will evaluate the effectiveness of two cooling methods for managing heat during physical activity: cooling bandanas and hand cooling tables. Studies have shown that cooling bandanas, which use special materials, can effectively reduce body heat by lowering the core temperature by about 0.3°C per minute, providing quick relief. Similarly, research suggests that cooling the palms with hand cooling tables can also lower core temperature after exercise. Known as palmar cooling, this method has been linked to better recovery and reduced body temperature. Participants in this trial will experience both methods to assess their effectiveness.16789
Who Is on the Research Team?
Julie Parsonnet, MD
Principal Investigator
Stanford University
Are You a Good Fit for This Trial?
This trial is for healthy adults who can safely participate in lab-based heat and exercise tests. People with health conditions that make it unsafe to be exposed to heat or do physical activity cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Biomarker Testing
Participants undergo biomarker testing to detect signs of heat strain
Cooling Intervention
Participants test cooling technologies including a cooling bandana and hand cooling table
Follow-up
Participants are monitored for any delayed effects of the interventions
What Are the Treatments Tested in This Trial?
Interventions
- Cooling bandana
- Hand cooling table
Trial Overview
Researchers are testing two cooling devices—a cooling bandana and a hand-cooling table—to see how well they help people cool down during simulated hot working conditions. They are also looking for blood markers that show signs of heat strain.
How Is the Trial Designed?
6
Treatment groups
Experimental Treatment
On day 1, participants use a hand cooling table after exercise for 10 minutes during a recovery period at a research laboratory while being monitored by trained research personnel. On day 2, participants use a cooling bandana during exercise for 1 hour. On day 3 participants use the treadmill for one hour and no cooling intervention is given to the participants.
On day 1, participants use a hand cooling table after exercise for 10 minutes during a recovery period at a research laboratory while being monitored by trained research personnel. On day 2 participants use the treadmill for one hour and no cooling intervention is given to the participants. On day 3, participants use a cooling bandana during exercise for 1 hour.
On day 1, participants use a cooling bandana during exercise for 1 hour at a research laboratory while being monitored by trained research personnel. On day 2, participants use a hand cooling table after exercise for 10 minutes during a recovery period. On day 3 participants use the treadmill for one hour and no cooling intervention is given to the participants.
On day 1, participants use a cooling bandana during exercise for 1 hour at a research laboratory while being monitored by trained research personnel. On day 2 participants use the treadmill for one hour and no cooling intervention is given to the participants. On day 3, participants use a hand cooling table after exercise for 10 minutes during a recovery period.
On day 1 participants use the treadmill for one hour at a research laboratory while being monitored by trained research personnel and no cooling intervention is given to the participants. On day 2, participants use a hand cooling table after exercise for 10 minutes during a recovery period. On day 3, participants use a cooling bandana during exercise for 1 hour.
On day 1 participants use the treadmill for one hour at a research laboratory while being monitored by trained research personnel and no cooling intervention is given to the participants. On day 2, participants use a cooling bandana during exercise for 1 hour. On day 3, participants use a hand cooling table after exercise for 10 minutes during a recovery period.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Citations
Cooling Solutions for Hyperthermia · Info for Participants
Research has shown that cooling bandanas, which use special cooling materials, effectively and safely provide relief from heat. Once soaked in water, they can ...
Cooling Techniques for Hyperthermia - StatPearls - NCBI - NIH
Cooling measures may be applied safely and effectively using equipment commonly available in the emergency department and selected prehospital ...
Cooling Techniques for Hyperthermia
It was reported in volunteers that it reduces core body temperature by approximately 0.3°C per minute; it reduced core body temperature ...
Current and Future Cooling Technologies Used in Preventing ...
Few data showing the effectiveness of cooling methods were found. Subjective ratings of perceived exertion were reportedly lowered with use ...
5.
costr.ilcor.org
costr.ilcor.org/document/first-aid-cooling-techniques-for-heat-stroke-and-exertional-hyperthermiaFirst Aid Cooling Techniques for Heat Stroke and Exertional ...
Outcomes: Mortality and rate of body temperature reduction (°C/min or °C/hour) were ranked as critical outcomes. Clinically important organ ...
Cooling bandana
Soak the bandana for five to nine minutes and stay cool for up to 72 hours. It keeps you cool through evaporation. The bandana features a ...
Safe cooling limits from exercise-induced hyperthermia
The objective of the study was to compare the three indices of core temperature and define safe cooling limits when using rectal temperature to avoid the ...
NCT06998667 | Cooling Solutions for Outdoor Workers
The investigators plan to test whether two active cooling technologies can help mitigate hyperthermia and risk for kidney injury.
9.
levitt-safety.com
levitt-safety.com/blog/heat-stress-solutions-technology?srsltid=AfmBOoopXt8RyiwosFTRI_ZiqPvi2R76gHkX8FjrJPTeyJoY1n8O0BbrHeat Stress Solutions & Technology
Cooling Bandana Headband: Crafted with advanced PVA cooling technology, this lightweight headband provides up to four hours of cooling relief. ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.