Indoor Air Quality Intervention for Cardiovascular Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new indoor air quality system called AIRWISE to determine its impact on heart health among older adults in wildfire-prone areas. The focus is on Montana, where worsening air quality from wildfires can affect heart health. Participants will use either the full AIRWISE system or portable air cleaners (PACs) and will monitor home air quality for a year. The trial seeks individuals aged 55-79 who do not smoke, do not live with smokers, and have not been diagnosed with heart disease. Participants should have a stable home setup with internet access for surveys. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance air quality and heart health for many.
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that this indoor air quality intervention is safe for older adults?
Research has shown that the AIRWISE program aims to improve indoor air quality through air filters, education, and practical tips. Studies have found that this approach can reduce indoor air pollution, benefiting heart health, particularly in older adults.
In past studies, researchers assessed the safety and effectiveness of AIRWISE by conducting health check-ups and air quality tests. No major negative effects have been directly linked to AIRWISE so far.
Overall, the AIRWISE system, which includes air purifiers and sensors, has proven user-friendly. It focuses on enhancing indoor air quality, which is crucial for those living in wildfire-affected areas.12345Why are researchers excited about this trial?
Researchers are excited about the AIRWISE intervention because it takes a comprehensive approach to improving indoor air quality, potentially reducing cardiovascular disease risk. Unlike standard air purifiers that just filter air, AIRWISE combines air purification with real-time air quality monitoring and educational tools to empower participants to make informed decisions. The integration of optical PM2.5 sensors and automated outdoor air quality alerts helps participants actively manage their indoor environment, potentially leading to better cardiovascular health outcomes.
What evidence suggests that this trial's interventions could be effective for cardiovascular disease?
Studies have shown that improving indoor air quality can enhance heart health. Research indicates that reducing tiny particles in the air helps lower blood pressure and body mass index (BMI), both crucial for heart health. In this trial, participants in the AIRWISE Intervention group will use air filters, education, and behavior tips to improve indoor air quality and heart health. Previous findings suggest these programs can effectively reduce risk factors for heart disease, especially in areas prone to wildfires. Meanwhile, participants in the PAC Control group will use portable air cleaners without additional AIRWISE equipment or education.12346
Are You a Good Fit for This Trial?
This trial is for adults aged 55-79 who live in their main home at least 5 days a week and have internet access, an email address, and an electronic device to complete surveys.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants in the AIRWISE Intervention group will use AIRWISE in their homes for 12 months, including PACs and PM2.5 sensors, while the PAC Control group will use PACs without additional equipment or education.
Follow-up
Participants are monitored for safety and effectiveness after treatment, including cardiovascular health assessments and air quality monitoring.
What Are the Treatments Tested in This Trial?
Interventions
- AIRWISE
- Portable Air Cleaner (PAC)
Trial Overview
The study compares two ways to improve indoor air quality: one group gets portable air cleaners plus interactive education (AIRWISE), while the other uses only portable air cleaners. The goal is to see if these help heart health in older adults exposed to wildfire smoke.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants randomized to the AIRWISE Intervention group will use AIRWISE in their homes for 12 months. The AIRWISE group will use two PACs to filter indoor air and two optical PM2.5 sensors with lights that change color in real time according to AQI. In addition, automated outdoor air quality alerts are sent via text and email when outdoor AQI goes above 75 (mid-point of the Moderate AQI category). Outdoor air quality will be referenced from the Environmental Protection Agency or PurpleAir monitor nearest to the participant's home. Based on the indoor and outdoor AQI levels, participants will reference a decision matrix and educational materials to make informed decisions on improving indoor air quality. Education and behavioral strategies are delivered through multiple approaches, including visual aids, handouts, videos, and a magnet with the decision matrix that can be placed in an accessible location in the home.
Participants randomized to the PAC Control group will use two PACs in their home without additional AIRWISE equipment/education. After randomization, they will be given instructions on study procedures and using the PAC units according to manufacturer recommendations. PAC Control group participants will not receive further education on air quality or recommendations on PAC use, nor will they receive additional equipment or outdoor AQI alerts. They will receive PurpleAir sensors without an AQI light that are for data collection purposes only, and they will not have access to the data throughout the study. Control participants will use and maintain the PACs at their own discretion. At the end of their participation, they will have the option of receiving the additional AIRWISE components.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Montana
Lead Sponsor
Citations
Evaluation of a Novel Indoor Air Pollution Intervention ...
Particulate matter air pollution is the leading environmental risk factor of cardiovascular disease and is increasing in the Western United States due to ...
Developing and Evaluating an Indoor Air Pollution ...
Developing and Evaluating an Indoor Air Pollution Intervention Among Cardiovascular Patients: the AIRWISE Study · Environmental Exposure.
AIRWISE Intervention for Cardiovascular Disease
The AIRWISE study tests an indoor air pollution intervention that includes air filtration systems, education, and behavior tips aimed at improving heart ...
Interventions to Reduce the Risk of Cardiovascular Disease ...
Interventions were effective for systolic (g = 0.66, 95% CI: 0.27-1.60) and diastolic blood pressure (g = 0.63, 95% CI: 0.21–1.06), and BMI (g = 0.71, 95% CI: ...
Indoor Air Quality Intervention for Cardiovascular Disease
Participants are monitored for safety and effectiveness after treatment, including cardiovascular health assessments and air quality monitoring.
Effects of long-term indoor air purification intervention on ...
Effects of long-term indoor air purification intervention on cardiovascular health in elderly: a parallel, double-blinded randomized controlled ...
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