Preference List Defaults for High Blood Pressure
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether altering how doctors view blood pressure medications on their computer systems can increase the prescription of combination medications. These medications can help patients adhere to treatment plans and reduce the number of pills they take. The trial compares two groups: one with an unchanged medication list and another where certain medications are marked as "(PREFERRED)" to appear first. Suitable participants include those prescribed medications like amlodipine or lisinopril during a clinic visit. As an unphased trial, this study provides an opportunity to improve prescription practices and potentially enhance treatment adherence for future patients.
Do I need to stop my current medications for this trial?
The trial information does not specify if you need to stop your current medications. It seems to focus on how medications are prescribed rather than changing what you currently take.
What prior data suggests that revising the preference list is safe for prescribing blood pressure medications?
Research has shown that combination blood pressure medications are usually well-tolerated by patients. Studies suggest that using a single pill combining two medications can simplify treatment and help patients adhere to their medication schedule. This approach reduces the number of pills to manage, lowering the chance of missing doses.
The American College of Cardiology and the American Heart Association recommend starting with a single pill that combines two blood pressure-lowering medications, especially for those with high blood pressure. This method is effective and aligns with current care guidelines.
Some people prefer taking separate pills to stop one if it causes side effects. However, combination pills are generally safe, with no significant increase in side effects compared to taking multiple separate medications.
In summary, while individual experiences may vary, combination blood pressure medications are generally safe and recommended for many people based on current research.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores a simple yet potentially powerful method to influence medication choices for high blood pressure. By adding "(PREFERRED)" next to certain combination medications in electronic health records, this approach aims to subtly guide healthcare providers to prescribe these options more often. Unlike developing new medications, this strategy focuses on changing prescribing behaviors in a way that's easy to implement and could lead to improved patient outcomes by promoting the use of effective combination therapies.
What evidence suggests that revising the preference list is effective for increasing the prescribing of combination blood pressure medications?
This trial will compare two approaches to managing high blood pressure using electronic health record (EHR) preference lists. Studies have shown that combination blood pressure medications effectively manage high blood pressure. Single-pill combinations often outperform multiple separate pills by simplifying adherence to treatment plans. Research has indicated that starting treatment with a two-drug combination is often optimal. This method can quickly lower blood pressure with fewer drugs, reducing the number of pills a patient needs. Many experts favor combination pills because they simplify treatment and improve long-term health. In this trial, one group will see no change to their EHR preference list, while another group will have "(PREFERRED)" added to combination medication names to potentially influence prescribing habits.23467
Are You a Good Fit for This Trial?
This trial is for adults (18+) who are being prescribed certain blood pressure medications during a clinic visit—either in-person, by phone, or virtually—at participating clinics. The prescription must be made by a clinical leader aware of the study.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Clinics are randomized to either a revised preference list with '(PREFERRED)' added to selected BP medications or no change to the preference list
Follow-up
Participants are monitored for changes in systolic and diastolic blood pressure, with follow-up readings taken 6 months to 1 year after enrollment
What Are the Treatments Tested in This Trial?
Interventions
- Revising preference list by adding "(PREFERRED)" to combination medication names
Trial Overview
The study tests if making combination blood pressure medicines more visible and labeling them as '(PREFERRED)' in the electronic prescribing system increases how often doctors choose these options for patients.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
"(PREFERRED)" will be added to the beginning of the preference list for selected BP medications, which will frequently cause these medications to be listed first.
Clinics will retain the usual EHR preference list order, with no changes to the default medication display.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Geisinger Clinic
Lead Sponsor
Citations
Single-Pill Combination Therapy for the Management of ...
The preferred approach of starting with single-pill combination medications (SPCMs) is more efficient, using fewer steps to achieve blood ...
Combination Therapy in Hypertension - PMC - NIH
Combinations of ≥3 drugs are not reviewed. Specific combinations are designated as preferred or acceptable based on the considerations previously outlined.
Single pill combination therapy for hypertension
There is strong proof that treating high blood pressure with appropriate drugs ... preferred strategy should be reduction of drug doses or the number of drugs.
4.
newsroom.heart.org
newsroom.heart.org/news/combination-pills-for-high-blood-pressure-may-simplify-treatment-improve-long-term-healthCombination pills for high blood pressure may simplify ...
Some clinicians prefer separate pills because it allows easier adjustment or discontinuation of an individual medication if adverse side effects ...
A Systematic Review of Patient Preferences, Expectations ...
According to the research by Mah et al, 51.4% of patients chose a collaborative role with a doctor, 44.8% preferred a passive role, and only 1.9 ...
Recommendations - NCBI - NIH
Long-acting antihypertensives are preferred. Examples of indications to consider specific agents include diuretics or CCBs in patients over 65 years or those of ...
Dual Combination Therapies in Treatment of Hypertension ...
However, current guidelines do not provide recommendations for the preferred choice of the second agent added to monotherapy, owing to the ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.