Financial Counseling and Health Reviews for Chronic Illness Management

(TIDES Trial)

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Pennsylvania
Must be taking: Once-daily oral medications
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Among adults with chronic illnesses like hypertension, diabetes, or HIV, adherence to daily oral medications is essential but often below 50%. Why do medication adherence and preventive health service engagement remain stubbornly low? Scarcity theory offers a novel explanation in the context of poverty. It posits that economic hardship imposes a cognitive burden that shifts attention from long-term goals to immediate needs, reduces future orientation (the relative value placed on immediate vs. future outcomes), and limits mental bandwidth (the cognitive resources needed for decisions), thus undermining behaviors like daily medication adherence and service engagement. To address these gaps, the study's objective is to rigorously test whether and how economic scarcity affects medication adherence and preventive service uptake among older adults with chronic disease, leveraging the naturally occurring monthly fluctuation in scarcity created by the Supplemental Nutrition Assistance Program (SNAP) benefit cycle as a natural experiment.

There are three aims:

1. Daily medication adherence will be measured objectively for four months with wireless electronic pill bottle caps (CleverCaps). The investigators will test whether, when, and by how much adherence changes as scarcity fluctuates during the SNAP benefit cycle.

2. The investigators will conduct two easily implementable RCTs to test whether scarcity affects participants' engagement with beneficial services requiring navigation of administrative burdens. In one trial, participants will be randomized to receive an invitation during either a high- or low- scarcity period (i.e., before vs. after SNAP receipt) to a personalized preventive health review that identifies gaps in US Preventive Services Task Force Grade A/B recommendations. In the second, participants will be invited to free financial counseling provided by the City of Philadelphia during a high- or low-scarcity period. The investigators hypothesize invitation response rates will be \>15% higher during low-scarcity periods.

3. Potential mechanisms that link scarcity with health behaviors will be examined by randomizing timing of validated measures of mental bandwidth and future orientation during a period of high- or low-scarcity (i.e., before vs. after SNAP receipt). The investigators hypothesize that there will be differences in several measures between participants who are randomly assessed during high- vs. low-scarcity periods (i.e. before vs. after SNAP receipt).

Impact: Demonstrating that scarcity helps to explain low medication adherence and beneficial health-related service uptake can inform patient-centered adherence interventions, clinical care-delivery approaches, health-system strategies, and public health approaches to improve these health behaviors and promote healthy aging.

Are You a Good Fit for This Trial?

This study is for adults with chronic illnesses like high blood pressure, type 2 diabetes, HIV/AIDS, or high cholesterol who receive SNAP benefits. Participants should be able to take daily medications and engage in health services.

Inclusion Criteria

I am 50 years old or older.
Resident of Philadelphia, Bucks, Montgomery, Chester, or Delaware County without plans to leave in the next 4 months
Self-report missing ≥2 doses of this medication over the prior 30 days (i.e., <94% adherence)
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Exclusion Criteria

Unable to provide consent
Non-English speaker
I have cognitive impairment as determined by my doctor.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Daily medication adherence is measured objectively for four months with wireless electronic pill bottle caps (CleverCaps). Participants are also randomized to receive invitations to preventive health reviews and financial counseling during high- or low-scarcity periods.

16 weeks

Follow-up

Participants are monitored for changes in mental bandwidth and future orientation through follow-up surveys conducted approximately 1 month after baseline visits.

4 weeks

What Are the Treatments Tested in This Trial?

Trial Overview

The trial tests if the timing of invitations for financial counseling or preventive health reviews—sent early or late in the SNAP benefit cycle—affects how likely people are to use these services and stick to their medication routines.

How Is the Trial Designed?

8

Treatment groups

Experimental Treatment

Group I: Late preventative health review, late financial counseling invitation, late aim 3 follow-up callExperimental Treatment3 Interventions
Group II: Late preventative health review, late financial counseling invitation, early aim 3 follow-up callExperimental Treatment3 Interventions
Group III: Late preventative health review, early financial counseling invitation, late aim 3 follow-up callExperimental Treatment3 Interventions
Group IV: Late preventative health review, early financial counseling invitation, early aim 3 follow-up callExperimental Treatment3 Interventions
Group V: Early preventative health review, late financial counseling invitation, late aim 3 follow-up callExperimental Treatment3 Interventions
Group VI: Early preventative health review, late financial counseling invitation, early aim 3 follow-up callExperimental Treatment3 Interventions
Group VII: Early preventative health review, early financial counseling invitation, late aim 3 follow-up callExperimental Treatment3 Interventions
Group VIII: Early preventative health review, early financial counseling invitation, early aim 3 follow-up callExperimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials
2,118
Recruited
45,270,000+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+