100 Participants NeededMy employer runs this trial

Pilates for Hypermobility Syndrome

(STABLE Trial)

SV
Overseen ByStephanie Voss, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Brigham and Women's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether Pilates can help reduce symptoms such as pain in people with hypermobility syndrome. Participants will either join weekly Pilates classes or attend educational seminars on managing hypermobility symptoms. The trial seeks adults who have experienced persistent pain related to hypermobility for at least three months and can move on and off the floor independently. As an unphased trial, it offers participants the chance to contribute to valuable research that could enhance symptom management for hypermobility syndrome.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that Pilates is safe for hypermobility syndrome?

Research has shown that Pilates is generally safe for people with hypermobility syndrome. In one study, participants who practiced Pilates reported less pain and improved physical function compared to those who did not. Another study found that Pilates enhanced muscle strength and reduced fatigue. Importantly, no serious side effects or harm were reported from practicing Pilates.

While Pilates is safe, working with an instructor who can adjust exercises for hypermobility is advisable. This ensures exercises are performed correctly and safely. Overall, Pilates appears to be a well-tolerated option for managing symptoms related to hypermobility.12345

Why are researchers excited about this trial?

Researchers are excited about using Pilates for hypermobility syndrome because it offers a physical, low-impact approach to managing symptoms, which is different from the standard treatments like pain management medications and physical therapy. Pilates focuses on strengthening core muscles and improving flexibility and balance, which could help stabilize joints and reduce discomfort for those with hypermobility. Additionally, Pilates-based exercise classes provide a structured, engaging way for patients to actively participate in their own symptom management, potentially leading to better adherence and outcomes compared to traditional methods.

What evidence suggests that Pilates might be an effective treatment for hypermobility syndrome?

Research has shown that Pilates can help people with hypermobility by reducing pain and improving body function. In this trial, participants in the Pilates group will attend once-weekly, in-person Pilates-based exercise classes for six weeks. One study found that people who practiced Pilates experienced less pain and moved better than those who did not. Another study demonstrated that Pilates can strengthen muscles and enhance the quality of life for children with joint hypermobility. Additionally, Pilates exercises have strengthened leg muscles and improved walking in individuals with knee hypermobility. Although improvements may be small, these findings suggest that Pilates could be a useful way to manage hypermobility symptoms.12346

Who Is on the Research Team?

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Samantha Meints, PhD

Principal Investigator

Brigham and Women's Hospital

Are You a Good Fit for This Trial?

This trial is for adults (18+) who have had ongoing pain for at least 3 months, report being hypermobile with a confirmed or suspected diagnosis of hEDS or HSD, rate their pain as at least 3 out of 10 in the past week, can get on and off the floor by themselves, speak English fluently, and can give written consent.

Inclusion Criteria

I have had ongoing pain for at least 3 months.
I am 18 years old or older.
* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS/HSD;
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 6 weeks of once weekly in-person Pilates-based exercise classes or educational seminars

6 weeks
6 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 weeks
2 visits (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Pilates

Trial Overview

The study is testing whether Pilates-based exercise combined with education helps reduce symptoms like pain in people with hypermobility conditions. Participants will follow a structured program to see if it improves their quality of life.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: PilatesExperimental Treatment1 Intervention
Group II: Enhanced Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Brigham and Women's Hospital

Lead Sponsor

Trials
1,694
Recruited
14,790,000+

Bernard Osher Foundation

Collaborator

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

Citations

An Online Pilates Program for People with Hypermobility - PMC

This online Pilates program for people with symptomatic hypermobility improved BIoH, BARQ, and TSK, though changes were modest. The exercises did not improve ...

Impact of a Pilates intervention on physical function in ...

Pilates may provide an effective intervention for children with GJH to reduce fatigue and improve muscle strength and HRQoL. Limited conclusions can be made ...

NCT07464093 | STABLE Pilates for Hypermobility

The Patient Reported Outcomes Measurement Information System Profile (PROMIS-29) will be used to assess pain intensity. Scores range from 8-40 with higher ...

Effectiveness of a prenatal pilates program on ligamentous ...

Participants in the Pilates group showed no significant changes in ligamentous laxity and joint hypermobility and reported minimal activity ...

Clarkson University Study Finds Online Pilates Program ...

The results showed that participants in the Pilates group reported less pain and better function compared with the comparison group. They also ...

Evaluating the Impact of a Pilates Intervention on Physical ...

This study aims to evaluate the impact of a Physiotherapy-led Pilates intervention on school aged children with HSD and the benefits of this approach on pain, ...