MR Evaluation for Brain Health
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to test a new MRI method to better understand how cerebral spinal fluid (CSF) moves in the brain. By observing CSF behavior, researchers hope to improve the diagnosis and understanding of brain diseases like Alzheimer's and hydrocephalus, a condition where fluid accumulates in the brain. The trial seeks healthy individuals without brain-related issues and those with suspected CSF problems or cognitive impairments, such as memory or balance issues. Participants must not have metal implants and must not be pregnant, as confirmed by a urine pregnancy test.
As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could enhance the understanding and diagnosis of brain diseases.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
What prior data suggests that this MR imaging method is safe for detecting CSF flow in the brain?
Research has shown that brain MRIs are generally very safe for most people. Unlike X-rays, MRIs do not use radiation, which is a common concern with other imaging tests. Instead, they use magnets and radio waves to capture images of the brain. As a result, there is no known risk of tissue harm from the scan itself.
However, safety checks are important before the scan. People with metal implants, pacemakers, or certain other medical devices often cannot undergo an MRI. The machine can be loud, but the noise is harmless. Overall, MRIs provide a safe and well-tolerated method for examining brain health.12345Why are researchers excited about this trial?
Researchers are excited about the MR brain evaluation because it offers a non-invasive way to assess brain health, which could potentially enhance early detection of neurological issues. Unlike other diagnostic tools, such as CT scans, MRIs don't use ionizing radiation, making them safer for repeated use. Additionally, the MRI's ability to provide detailed images of the brain's structure and function could lead to more accurate diagnoses and personalized treatment plans. This approach could pave the way for better understanding and management of various brain conditions.
What evidence suggests that this MR imaging method is effective for detecting CSF flow in the brain?
Research has shown that Magnetic Resonance Imaging (MRI) effectively detects changes in the brain. It identifies issues related to conditions such as alcoholism and dementia. MRI also predicts recovery prospects after a stroke by assessing brain health indicators. This imaging method produces detailed brain images, linking brain structures with behavior or symptoms. Overall, MRI serves as a powerful tool for diagnosing and understanding brain-related issues. Participants in this trial will undergo MR imaging of the brain to evaluate these aspects of brain health.678910
Who Is on the Research Team?
Petrice Cogswell, MD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
This trial is for healthy individuals and those with suspected altered CSF dynamics, such as hydrocephalus or cognitive impairments like Alzheimer's. Participants should not have conditions affecting brain function or memory issues. Pregnant women, people needing sedation for MRI, or those with non-MRI compatible devices cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
MR Imaging
Participants undergo MR imaging to measure CSF flow and volume, and assess white matter disease
Follow-up
Participants are monitored for any immediate post-imaging effects and data analysis
What Are the Treatments Tested in This Trial?
Interventions
- MR Brain
- Urine Pregnancy Test
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor