Mindfulness-Based Stress Reduction for HS

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Francisco
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a mindfulness-based stress reduction program for individuals with hidradenitis suppurativa (HS), a condition that causes painful skin abscesses and nodules. The researchers aim to determine if mindfulness practices can reduce stress and improve quality of life for those with HS. Participants must have an HS diagnosis from a dermatologist and reliable internet access to join the study activities. As an unphased trial, this study offers a unique opportunity to explore innovative stress reduction techniques that may enhance participants' quality of life.

What prior data suggests that this mindfulness-based stress reduction program is safe for patients with HS?

Research has shown that Mindfulness-Based Stress Reduction (MBSR) is generally safe for participants. Studies have found that MBSR can enhance mental health and reduce stress without harmful effects. For example, one study found that MBSR lowered stress levels and improved mindfulness, which involves focusing on the present moment without judgment. Another study with asthma patients showed that MBSR improved their health, indicating it is well-tolerated.

Although MBSR is not a medication, it includes practices like meditation and breathing exercises, which are not known to cause negative effects. Overall, MBSR appears to be a safe way to manage stress and improve quality of life.12345

Why are researchers excited about this trial?

Mindfulness-Based Stress Reduction (MBSR) is unique for treating Hidradenitis Suppurativa (HS) because it focuses on managing stress, which is thought to be a trigger for flare-ups. Unlike typical HS treatments like antibiotics, biologics, or surgery that target symptoms directly, MBSR uses meditation, yoga, and mindfulness exercises to potentially reduce stress and improve overall well-being. Researchers are excited about MBSR because it offers a non-invasive, holistic approach that could enhance quality of life and possibly reduce the severity or frequency of HS symptoms by addressing a root cause.

What evidence suggests that mindfulness-based stress reduction is effective for hidradenitis suppurativa?

Research has shown that mindfulness practices, such as the Mindfulness-Based Stress Reduction (MBSR) program, can help manage chronic illnesses by reducing stress and pain. This trial will evaluate the effects of MBSR on individuals with hidradenitis suppurativa (HS). Studies suggest that meditation, a key component of mindfulness, can improve focus and concentration, potentially benefiting people with conditions like HS. Since HS is often linked to increased anxiety and depression, reducing stress is crucial for managing the condition. MBSR has supported positive health changes, which might help those living with HS manage their symptoms better. Although specific data on MBSR's effect on HS is limited, research strongly supports the overall benefits of stress reduction and mindfulness.678910

Who Is on the Research Team?

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Aileen Y Chang, MD

Principal Investigator

University of California, San Francisco

Are You a Good Fit for This Trial?

This trial is for people diagnosed with hidradenitis suppurativa (HS), a chronic skin condition. Participants should be willing to try a mindfulness program and provide feedback. Specific inclusion or exclusion criteria are not detailed.

Inclusion Criteria

Able to read, write, and speak English
Access to a device with Internet access
I have been diagnosed with hidradenitis suppurativa by a dermatologist.
See 1 more

Exclusion Criteria

Lacks reliable access to the Internet or device (e.g., phone, tablet, laptop/computer) to participate in study activities
Unable to confirm HS diagnosis by a dermatologist

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo a Mindfulness-Based Stress Reduction (MBSR) program tailored for Hidradenitis Suppurativa, delivered virtually over Zoom

8 weeks
8 virtual sessions

Follow-up

Participants are monitored for changes in mindfulness, quality of life, and stress levels after the intervention

12 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Mindfulness-Based Stress Reduction

Trial Overview

The study is testing a mindfulness-based stress reduction (MBSR) program designed specifically for people with HS, aiming to see if it helps reduce stress and improve quality of life.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Intervention ArmExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

Citations

The Burden of Hidradenitis Suppurativa Signs and ...

Unfortunately, current HS therapies often provide inadequate pain relief, and studies of HS pain-directed therapies are sparse. Non ...

News Archive

New Phase 2 data suggest that topical ruxolitinib cream may help address a major unmet need in mild-to-moderate hidradenitis suppurativa. Patients treated with ...

International Association of Hidradenitis Suppurativa Network

Research shows that mindfulness supports general health behavior change including the ability to manage chronic illness. Initiating and then maintaining ...

Meditation to Aid Hidradenitis Suppurativa

Research shows that the practice of meditation as an effective tool for managing stress, improving focus, concentration and reducing pain.

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pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/38589980/

The impact of hidradenitis suppurativa on work productivity ...

Conclusions: Current evidence suggests considerable impairment of workplace functioning in patients with HS. Our findings point to a significant ...

The Impact of Mindfulness-Based Stress Reduction ...

This study aimed to evaluate the effect of MBSR therapy on mindfulness and mental health (assessed via SCL-90 and MAAS scales) in adolescents ...

Asthma Outcomes Improved With Use of Mindfulness ...

Training patients with asthma in mindfulness-based stress reduction improves clinically relevant outcomes and may therefore enhance asthma ...

Mindfulness Training Hidradenitis Suppurativa (HS) - Clin...

The purpose of this research is to investigate the effectiveness of mindfulness training on the quality of life of Hidradenitis Suppurativa ...

Effect of Mindfulness-Based Stress Reduction on the Well ...

MBSR was able to lower distress levels, except for depersonalization, which increased, while emotional exhaustion decreased in the group enrolled in the last ...

Mindfulness Based Stress Reduction as an Adjunctive ...

Mindfulness Based Stress Reduction (MBSR) for patients reporting high stress levels;outcomes include changes in inflammatory processes in the skin;cytokine ...