Exercise Programs for Hidradenitis Suppurativa

This trial aims to design and test exercise programs for people with hidradenitis suppurativa (HS), a skin condition that causes painful lumps. Researchers seek to understand the challenges HS patients face with physical activity and explore how exercise can help. Participants will follow either a personalized home exercise program for up to 12 weeks or a shorter exercise program. The trial seeks individuals diagnosed with moderate-to-severe HS by a dermatologist. As an unphased trial, it offers participants the chance to contribute to innovative research that could enhance exercise recommendations for HS patients.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.

Research shows that home-based exercise programs are generally safe. These programs have been tested in other conditions, such as a type of muscular dystrophy, and have been well-received. For individuals with hidradenitis suppurativa (HS), the main concerns with exercise are sweating and pain. While sweating is a normal part of exercising, it can be uncomfortable for those with HS. However, these exercise programs have not revealed any serious safety issues. Participants in similar studies successfully managed these concerns.¹²³⁴⁵

Researchers are excited about the exercise programs being studied for hidradenitis suppurativa because they're exploring a non-drug approach to manage this challenging skin condition. Most current treatments focus on medications like antibiotics, biologics, or surgery to reduce inflammation and manage symptoms. However, these exercise programs aim to improve patients' quality of life through physical activity, potentially reducing flare-ups and pain. The Home Exercise Program offers a personalized routine that participants can follow at home for up to 12 weeks, providing flexibility and convenience. The Short Exercise Program serves as a comparator, allowing researchers to evaluate the effectiveness of different exercise durations and intensities.

This trial will compare two exercise programs for managing symptoms of hidradenitis suppurativa (HS), a long-term skin condition. Participants in one arm will follow a Home Exercise Program, a personalized plan designed to be safe and effective for people with HS. Another arm will involve a Short Exercise Program. Research has shown that exercise can improve skin health by reducing inflammation and enhancing overall well-being. However, some people find exercise difficult due to sweating and pain, so personalized exercise plans that address these challenges can be beneficial. Regular physical activity has also been proven to help with chronic pain, which is common for those with HS.¹²³⁶⁷