Dissolving vs Permanent Stitches for Inguinal Hernia

This trial tests two types of stitches, dissolving and permanent, to determine which is more effective for repairing a groin hernia without mesh. Researchers aim to discover if dissolving stitches (Polydioxanone suture, PDS) cause less long-term discomfort and are equally effective at preventing hernia recurrence within a year. The trial is open to adults with a single-sided groin hernia who can consent and have a BMI of 30 or less. Participants will have their hernia repaired using one of the stitch types, chosen randomly during surgery, and will complete follow-up visits and questionnaires about their recovery and quality of life. As an unphased trial, this study offers a unique opportunity to contribute to medical knowledge and potentially improve future hernia repair techniques.

Research has shown that polydioxanone (PDS) stitches are generally safe and might cause less groin pain after surgery compared to nonabsorbable stitches like polypropylene (Prolene). Studies have found that PDS stitches can reduce the risk of wound problems, making them a well-accepted choice for hernia repairs.

In contrast, Prolene stitches, which remain in the body permanently, have been linked to more cases of long-term groin pain after surgery. Despite this, they are often used for their strength and durability.

Researchers are excited about this trial because they want to find out whether dissolving stitches, like polydioxanone (PDS), offer better outcomes than permanent stitches, such as polypropylene (Prolene), for inguinal hernia repairs. Unlike permanent stitches, which stay in the body indefinitely, PDS stitches gradually dissolve over time, potentially reducing the risk of long-term complications like infection or discomfort. This trial could highlight whether PDS offers quicker recovery and fewer issues compared to the traditional permanent options, sparking interest in refining surgical techniques for improved patient care.

This trial will compare polydioxanone (PDS) stitches, which dissolve slowly, with polypropylene (Prolene) stitches, which are permanent, in inguinal hernia repairs. Research has shown that PDS stitches might reduce long-term discomfort after hernia repairs. Early findings suggest that dissolving stitches like PDS could lessen the sensation of having a foreign object in the body, a common issue with permanent stitches. In contrast, Prolene stitches have been widely used in hernia repairs and have consistently prevented hernias from returning. While Prolene is trusted for its effectiveness in stopping hernias from recurring, researchers in this trial are exploring whether PDS can offer similar benefits with less discomfort.⁶⁷⁸⁹¹⁰