BOLD-MRI for Liver Cancer
(BOLDMRI Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to find out whether a special type of magnetic resonance imaging ( MRI), called blood oxygen level-dependent (BOLD) MRI, can help measure how much oxygen is present in liver tumors. Tumors with low oxygen levels are described as being hypoxic.
Yttrium-90 (Y-90) is a type of radioactive material used to treat liver tumors, including hepatocellular carcinoma (HCC), a type of liver cancer. Y-90 is a form of radiation treatment delivered directly to liver tumors through tiny beads carried by blood vessels. These beads release radiation that damages and kills cancer cells while helping limit radiation exposure to surrounding healthy tissue. This treatment is also called Y-90 radioembolization or selective internal radiation therapy (SIRT).
Who Is on the Research Team?
Bryan Harris, MD
Principal Investigator
UNC Lineberger Comprehensive Cancer Center
Alexander Villalobos, MD
Principal Investigator
UNC Lineberger Comprehensive Cancer Center
Are You a Good Fit for This Trial?
This trial is for people with liver cancer, specifically hepatocellular carcinoma. Participants should be candidates for Y-90 radioembolization treatment and able to undergo MRI scans. Detailed inclusion or exclusion criteria are not provided.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Yttrium-90 (Y-90) Radioembolization
Trial Overview
The study uses a special MRI scan (BOLD-MRI) to measure oxygen levels in liver tumors before Y-90 radioembolization treatment, aiming to see if this imaging can predict how well the tumor will respond to therapy.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Patients with hepatocellular carcinoma (HCC) who are scheduled to receive Y-90 selective internal radiation therapy (SIRT),
Find a Clinic Near You
Who Is Running the Clinical Trial?
UNC Lineberger Comprehensive Cancer Center
Lead Sponsor
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