Arterial Embolization vs Band Ligation for Hemorrhoids

(STRATOS Trial)

This trial aims to determine which of two treatments for hemorrhoid bleeding is more effective: hemorrhoidal artery embolization (HAE) or rubber band ligation (RBL). HAE involves using a catheter to block blood flow to the hemorrhoid, while RBL uses small rubber bands to cut off the blood supply. The trial seeks to identify which method better reduces symptoms and improves quality of life. Individuals who have experienced ongoing bleeding from internal hemorrhoids, despite trying other treatments like fiber or creams, may be suitable candidates for the trial. As an unphased trial, this study provides an opportunity to contribute to medical knowledge and potentially find relief from persistent symptoms.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Previous studies have shown that hemorrhoidal artery embolization (HAE) safely treats hemorrhoids. Most patients experienced only minor side effects, and the procedure was well-received. It succeeded in 93% of patients, though some required repeat procedures. This minimally invasive procedure has a strong safety record.

Rubber band ligation (RBL) is also considered safe for treating hemorrhoids. Research shows it is effective in about 80% to 89% of cases. The procedure is simple and generally well-tolerated, though some patients may experience severe anal pain. Infections are rare but possible. Overall, RBL is widely used and effective for many people.

Researchers are excited about these treatments for hemorrhoids because they offer innovative methods for reducing discomfort and improving recovery. Hemorrhoidal Artery Embolization is unique because it uses a catheter to insert tiny particles or coils into the blood vessel feeding the hemorrhoid, cutting off blood flow and causing it to shrink. This minimally invasive technique could reduce recovery time compared to traditional surgeries. Rubber Band Ligation, while a more established procedure, is gaining attention for its simplicity and effectiveness, using a band to cut off blood flow, which causes the hemorrhoid to shrink and fall off. These methods aim to provide less invasive, quicker recovery options compared to standard surgical treatments.

This trial will compare two treatments for hemorrhoids: hemorrhoidal artery embolization (HAE) and rubber band ligation (RBL). Research has shown that HAE effectively reduces hemorrhoid symptoms in about 93% of patients after one month. It is also considered safe and provides long-lasting relief. Meanwhile, RBL improves symptoms in about 89% of patients and is generally well-tolerated. Both treatments work by cutting off blood flow to the hemorrhoids, causing them to shrink. Participants in this trial will receive one of these treatments to evaluate their effectiveness.¹³⁴⁵⁶