Peer Support for Bone Marrow Transplant
(STEPP-3 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This randomized clinical trial is evaluating the impact of a structured peer support intervention (STEPP) on psychological distress and quality of life among patients undergoing hematopoietic stem cell transplantation.
Are You a Good Fit for This Trial?
This trial is for adults who are about to have a bone marrow (stem cell) transplant. Participants should be able to take part in support sessions and not have conditions that would prevent them from joining, as determined by the study team.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-Transplant Intervention
Participants receive five manualized phone sessions of the STEPP intervention prior to transplantation
Acute Recovery
Participants continue to receive STEPP intervention through acute recovery post-transplantation
Follow-up
Participants are monitored for psychological distress, quality of life, self-efficacy, social support, and anxiety symptoms
What Are the Treatments Tested in This Trial?
Interventions
- STEPP
Trial Overview
The study compares two groups: one receives structured peer support (STEPP), where patients connect with trained peers, and the other gets standard care with minimal extra support. The goal is to see if peer support helps reduce stress and improve quality of life.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Participants recruited from the Dana-Farber Cancer Institute, Moffitt Cancer Center, and Fred Hutchinson Cancer Center who are randomized to the intervention/experimental arm will receive the STEPP intervention, which pairs patients preparing for their transplant hospitalization with hematopoietic stem cell transplantation (HSCT) survivors for informational, emotional, and practical support. Participants will complete questionnaires (in person, over the computer or telephone, or by mail) at predetermined days per protocol.
Participants recruited from the Dana-Farber Cancer Institute, Moffitt Cancer Center, and Fred Hutchinson Cancer Center who are randomized to the minimally enhanced usual care control arm will receive standard psychosocial care provided by social work plus a comprehensive list of local, regional, and national peer support resources. Participants will complete questionnaires (in person, via computer or telephone, or by mail) at predetermined days per protocol.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor
Dana-Farber Cancer Institute
Collaborator
H. Lee Moffitt Cancer Center and Research Institute
Collaborator
Fred Hutchinson Cancer Center
Collaborator
National Cancer Institute (NCI)
Collaborator
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